中山醫學大學機構典藏 CSMUIR:Item 310902500/4374
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    题名: The association between polypronucleate zygote formation with certain motion characteristics of sperm and IVF outcome
    作者: Lee, Tsung-Hsien
    Liu, Chung-Hsien
    Huang, Chun-Chia
    Chen, Hsui-Hui
    Chen, Shee-Uan
    Lee, Maw-Sheng
    贡献者: 中山醫學大學
    醫學系
    关键词: In vitro fertilization
    Computer assisted semen analysis
    Normal fertilization
    Polypronucleate zygotes
    日期: 2008
    上传时间: 2012-07-24T09:16:41Z (UTC)
    ISSN: 1058-0468
    摘要: Purpose
    To determine the efficiency of sperm motion characteristics as predictors for normal (2PN) and polypronulceate (PPN) zygotes in IVF.
    Methods
    A retrospective cohort analysis for a total of 230 couples undergoing IVF treatment in a single infertility center.
    Result(s)
    Subsequent to semen analysis and hemizona assay, unexpected fertilization failure would appear to have occurred only extremely rarely (1/236, 0.4%). The rate of PPN, however, did arise and appeared to be related to certain sperm motion characteristics, such as lateral head displacement and concentration of progressive motile sperm. Interestingly, the patients featuring a high PPN rate (>20%) was associated with a greater pregnancy rate than those featuring a low PPN rate (<20%).
    Conclusion
    The sperm motion characteristics examined herein could be utilized to predict the rate of PPN in IVF. In order to enhance the rate of 2PN and maintain the relative high rate of clinical pregnancy, an efficient method needs further investigation and development.
    URI: https://ir.csmu.edu.tw:8080/ir/handle/310902500/4374
    http://dx.doi.org/10.1007/s10815-007-9190-1
    關聯: Journal of Assisted Reproduction and Genetics
    Volume 25, Number 1 (2008), 35-41
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