中山醫學大學機構典藏 CSMUIR:Item 310902500/3604
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    题名: Bacteriology and antimicrobial susceptibility of pediatric chronic rhinosinusitis: a 6-year result of maxillary sinus punctures
    作者: Chung-Han Hsin;Mao-Chang Su;Chien-Han Tsao;Chun-Yi Chuang;Chia-Ming Liu
    贡献者: 中山醫學大學:醫學系
    日期: 2010
    上传时间: 2011-03-14T03:51:34Z (UTC)
    ISSN: 0196-0709
    摘要: Purpose:Few studies in the past decade have focused on antimicrobial resistance of bacteria in pediatric rhinosinusitis. This study aimed to characterize organisms cultured from pediatric chronic rhinosinusitis, as well as current resistance patterns of pathogens.
    Materials and methods:The study was conducted from January 2001 to December 2006. Children with radiograph-proven chronic rhinosinusitis underwent maxillary sinus punctures to obtain pathogens and for analysis of antibiotic resistance.
    Results:The total 295 cultures obtained from 165 children yielded 399 isolates. The most common isolates were α-hemolytic Streptococcus (20.8%), Haemophilus influenzae (19.5%), Streptococcus pneumoniae (14.0%), coagulase-negative Staphylococcus (13.0%), and Staphylococcus aureus (9.3%). Anaerobes accounted for 8.0% of all isolates. Susceptibility rates of H influenzae for ampicillin and co-trimoxazole were 44.7% and 42.1%, respectively, in the first 3 years of the study and 25% and 40%, respectively, in the next 3 years. Susceptibility rates of S pneumoniae were 83.3% for penicillin, 0% for erythromycin, and 33.3% for clindamycin in the first 3 years and 73.7%, 5.3%, and 28.9%, respectively, in the latter 3 years.
    Conclusion:This study showed a different pattern of antibiotic resistance in pediatric chronic rhinosinusitis as compared with previous studies in both children and adults. The resistance rate of H influenzae for ampicillin appears to be a growing problem in pediatric rhinosinusitis.
    URI: https://ir.csmu.edu.tw:8080/handle/310902500/3604
    http://dx.doi.org/10.1016/j.amjoto.2008.11.014
    關聯: American Journal of Otolaryngology,Volume 31, Issue 3, May-June 2010, Pages 145-149
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