Effects of Vigiis 101-LAB on a healthy population's gut microflora, peristalsis, immunity, and anti-oxidative capacity: A randomized, double-blind, placebo-controlled clinical study

doi:10.1016/j.heliyon.2020.e04979

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Please use this identifier to cite or link to this item: https://ir.csmu.edu.tw:8080/ir/handle/310902500/24650

Title:	Effects of Vigiis 101-LAB on a healthy population's gut microflora, peristalsis, immunity, and anti-oxidative capacity: A randomized, double-blind, placebo-controlled clinical study
Authors:	Chen, CL;Liou, JM;Lu, TM;Lin, YH;Wang, CK;Pan, TM
Keywords:	Microbiology;Food microbiology;Nutrition;Evidence-based medicine;Gut microflora;Immunity;Anti-oxidative capacity;Lactobacillus paracasei subsp. paracasei NTU 101;Probiotics
Date:	2020
Issue Date:	2022-08-09T08:05:47Z (UTC)
Publisher:	ELSEVIER SCI LTD
Abstract:	Vigiis 101-LAB capsules are produced from the fermentation of Lactobacillus paracasei subsp. paracasei NTU 101. We tested effects of Vigiis 101-LAB capsules I or II (5 or 10 billion CFU/day, respectively) on gut microflora in clinical trial I, and on peristalsis, immunity, and anti-oxidative capacity in clinical trial II, during a 4-week randomized, double-blind, placebo-controlled, adaptive-design study. In trial I, 36 subjects were divided into capsule I and placebo groups. After 4 weeks, Bifidobacterium spp. and Lactobacillus spp. counts were significantly higher in the feces of treatment subjects, with increases of 4.01- and 4.25-fold, respectively. In trial II, 52 subjects were divided into capsule II and placebo groups. After 4 weeks, the treatment group was found to have improved motility, decreased food transit time, and significantly increased immunoglobulin G, immunoglobulin M, and antioxidant activity. Thus, daily administration of Vigiis 101 capsule II can improve peristalsis, immunity, and anti-oxidative capacity.
URI:	http://dx.doi.org/10.1016/j.heliyon.2020.e04979 https://www.webofscience.com/wos/woscc/full-record/WOS:000579136000210 https://ir.csmu.edu.tw:8080/handle/310902500/24650
Relation:	HELIYON ,2020 ,v6 ,issue 9
Appears in Collections:	[researcher portal] Artical

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