Study protocol to investigate the correlation between Tourette syndrome and allergy in children and adolescents

doi:10.1177/0300060520973921

中山醫學大學機構典藏 CSMUIR > 中山醫學大學研究成果 > 期刊論文 > Item 310902500/24440

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题名:	Study protocol to investigate the correlation between Tourette syndrome and allergy in children and adolescents
作者:	Tsai, LH;Lin, JW;Lue, KH
关键词:	Allergen;allergic disease;neuropsychiatric disorders;Tourette syndrome;children and adolescents;survey
日期:	2020
上传时间:	2022-08-09T08:02:20Z (UTC)
出版者:	SAGE PUBLICATIONS LTD
ISSN:	0300-0605
摘要:	Objective Noting that the usefulness of cases diagnosed in administrative registers is dependent on diagnostic validity, in this study, we aim to elucidate the correlation between Tourette syndrome and allergy in children and adolescents, specifically with regard to incidence of asthma, allergic rhinitis, allergic conjunctivitis, and atopic dermatitis. Methods Based on a set of inclusion and exclusion criteria, we intend to enroll 200 children and adolescents aged 18 years and younger, accompanied by their parents, for a duration of 2 years. We will administer an anonymous questionnaire in a case-control study. We will use the chi-squared test to evaluate differences between cases and controls. Results According to the European Review for Medical and Pharmacological Sciences, the proportion of allergic diseases expected in patients with Tourette syndrome is 53.1% (17/32) and 22.9% (8/35) in the controls. Setting the type 1 error to 0.05 and the power to 0.8, we will ensure a 1:2 case-to-control ratio. Conclusions This study protocol describes our analysis of anonymous questionnaire responses. Comorbidity rates, environmental factors, and genetic factors for various allergens, allergies, and other neuropsychiatric disorders will be studied.
URI:	http://dx.doi.org/10.1177/0300060520973921 https://www.webofscience.com/wos/woscc/full-record/WOS:000596408500001 https://ir.csmu.edu.tw:8080/handle/310902500/24440
關聯:	JOURNAL OF INTERNATIONAL MEDICAL RESEARCH ,2020 ,v48 ,issue 12
显示于类别:	[中山醫學大學研究成果] 期刊論文

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