中山醫學大學機構典藏 CSMUIR:Item 310902500/24326
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    题名: Birth defects in Taiwan: A 10-year nationwide population-based, cohort study
    作者: Chen, LJ;Chiou, JY;Huang, JY;Su, PH;Chen, JY
    关键词: Birth defect;ICD-9-CM code;Prevalence;Relative risk
    日期: 2020
    上传时间: 2022-08-09T08:00:28Z (UTC)
    出版者: ELSEVIER TAIWAN
    ISSN: 0929-6646
    摘要: Background/Purpose: Birth defects (BDs) are main causes of mortality and disability in infants and children. The aims of this study were to analyze the prevalence, types and risk factors of BDs in Taiwan. Methods: Data of all births (including live and stillbirths), types, characteristics, and associated risk factors of BDs were obtained from the National Birth Registry and National Health Insurance Research Data base in Taiwan between 2005 and 2014. Birth defects were coded according to International Classification of Diseases 9th Revision-Clinical Modification codes 740-759. Results: A total of 55,299 infants were diagnosed as having BDs among 2,033,004 births. The prevalence of BDs was 271.66 per 10,000 births. The prevalence of BDs did not change significantly between 2005 and 2014, there was a higher birth rate and lower BDs in 2012 (year of dragon) in Taiwan. The most common type of BDs was cardiovascular abnormalities, and ventricular septal defect was the most common disease. Extreme maternal age (<18 years or >= 30 years), preterm, and low birth weight were associated with BDs. Maternal diseases associated with BDs included hypertension, cardiovascular diseases, renal diseases, genitourinary infections, anemia, mental disorders, and diabetes mellitus. Conclusion: The prevalence of BDs was 271.66 per 10,000 births. The most common types of BDs were cardiovascular abnormalities. If we can reduce maternal chronic diseases, we will decrease the prevalence of BDs. Copyright (C) 2019, Formosan Medical Association. Published by Elsevier Taiwan LLC.
    URI: http://dx.doi.org/10.1016/j.jfma.2019.08.006
    https://www.webofscience.com/wos/woscc/full-record/WOS:000504758400023
    https://ir.csmu.edu.tw:8080/handle/310902500/24326
    關聯: JOURNAL OF THE FORMOSAN MEDICAL ASSOCIATION ,2020 ,v119 ,issue 1 ,p553-559
    显示于类别:[中山醫學大學研究成果] 期刊論文

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