Long Non-Coding RNA MEG3 in Cellular Stemness

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題名:	Long Non-Coding RNA MEG3 in Cellular Stemness
作者:	Hsieh, PF;Yu, CC;Chu, PM;Hsieh, PL
關鍵詞:	long non-coding RNA MEG3;embryonic stem cells;mesenchymal stem cells;cancer stem cells
日期:	2021
上傳時間:	2022-08-05T10:44:44Z (UTC)
出版者:	MDPI
摘要:	Long non-coding RNAs (lncRNAs) regulate a diverse array of cellular processes at the transcriptional, post-transcriptional, translational, and post-translational levels. Accumulating evidence suggests that lncRNA MEG3 exerts a large repertoire of regulatory functions in cellular stemness. This review focuses on the molecular mechanisms by which lncRNA MEG3 functions as a signal, scaffold, guide, and decoy for multi-lineage differentiation and even cancer progression. The role of MEG3 in various types of stem cells and cancer stem cells is discussed. Here, we provide an overview of the functional versatility of lncRNA MEG3 in modulating pluripotency, differentiation, and cancer stemness.
URI:	http://dx.doi.org/10.3390/ijms22105348 https://www.webofscience.com/wos/woscc/full-record/WOS:000662011800001 https://ir.csmu.edu.tw:8080/handle/310902500/24202
關聯:	INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES ,2021 ,v22 ,issue10
顯示於類別:	[中山醫學大學研究成果] 其他文獻

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