中山醫學大學機構典藏 CSMUIR:Item 310902500/24202
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    题名: Long Non-Coding RNA MEG3 in Cellular Stemness
    作者: Hsieh, PF;Yu, CC;Chu, PM;Hsieh, PL
    关键词: long non-coding RNA MEG3;embryonic stem cells;mesenchymal stem cells;cancer stem cells
    日期: 2021
    上传时间: 2022-08-05T10:44:44Z (UTC)
    出版者: MDPI
    摘要: Long non-coding RNAs (lncRNAs) regulate a diverse array of cellular processes at the transcriptional, post-transcriptional, translational, and post-translational levels. Accumulating evidence suggests that lncRNA MEG3 exerts a large repertoire of regulatory functions in cellular stemness. This review focuses on the molecular mechanisms by which lncRNA MEG3 functions as a signal, scaffold, guide, and decoy for multi-lineage differentiation and even cancer progression. The role of MEG3 in various types of stem cells and cancer stem cells is discussed. Here, we provide an overview of the functional versatility of lncRNA MEG3 in modulating pluripotency, differentiation, and cancer stemness.
    URI: http://dx.doi.org/10.3390/ijms22105348
    https://www.webofscience.com/wos/woscc/full-record/WOS:000662011800001
    https://ir.csmu.edu.tw:8080/handle/310902500/24202
    關聯: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES ,2021 ,v22 ,issue10
    显示于类别:[中山醫學大學研究成果] 其他文獻

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