Younger adults with mild-to-moderate COVID-19 exhibited more prevalent olfactory dysfunction in Taiwan

doi:10.1016/j.jmii.2021.01.006

中山醫學大學機構典藏 CSMUIR > 中山醫學大學研究成果 > 期刊論文 > Item 310902500/23552

Please use this identifier to cite or link to this item: https://ir.csmu.edu.tw:8080/ir/handle/310902500/23552

Title:	Younger adults with mild-to-moderate COVID-19 exhibited more prevalent olfactory dysfunction in Taiwan
Authors:	Cheng, MY;Hsih, WH;Ho, MW;Lai, YC;Liao, WC;Chen, CY;Chen, TC;Lee, YL;Liu, PY;Kao, CC;Chou, CH;Lin, PC;Chi, CY;Leong, LY;Tai, CJ;Lu, MC
Keywords:	Olfactory dysfunction;Taiwan smell identification test (TWSIT);Mild-to-moderate;COVID-19 patients
Date:	2021
Issue Date:	2022-08-05T09:39:07Z (UTC)
Publisher:	ELSEVIER TAIWAN
ISSN:	1684-1182
Abstract:	Background: Coronavirus Disease 2019 (COVID-19) is rapidly transmitted from per-son to person, causing global pandemic since December 2019. Instantly detecting COVID-19 is crucial for epidemic prevention. In this study, olfactory dysfunction is a significant symptom in mild to moderate COVID-19 patients but relatively rare in other respiratory viral infections. The Taiwan smell identification test (TWSIT) is a speedy and inexpensive option for accurately distinguishing anosmia that also quantifies the degree of anosmia. Using TWSIT in the outpa-tient clinic for early identifying the patients with mild to moderate COVID-19 can be promising. Methods: Nineteen patients confirmed COVID-19 in central Taiwan were collected and divided into two groups: olfactory dysfunction and non-olfactory dysfunction. Demographic character-istics, laboratory findings, and the results of the olfactory test were compared between these two groups . Findings: Thirteen (68.4%) of the 19 patients had olfactory dysfunction. The patients with ol-factory dysfunction were younger than those without this symptom. The statistical difference in age distribution was significant between these two groups (IQR: 25.5-35.5 vs. IQR: 32.5-60.3; p-value: 0.012). There was no significant difference in gender, smoking history, comor-bidities, travel history, respiratory tract infection symptoms, and laboratory findings between these two groups. Conclusion: This study demonstrated that young adults were prone to develop olfactory dys-functions. In the flu season, olfactory dysfunction is considered a specific screening criterion for early detecting COVID-19 in the community. TWSIT can serve as a decent test for quanti-fying and qualifying olfactory dysfunction. Copyright (c) 2021, Taiwan Society of Microbiology. Published by Elsevier Taiwan LLC. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
URI:	http://dx.doi.org/10.1016/j.jmii.2021.01.006 https://www.webofscience.com/wos/woscc/full-record/WOS:000708390100004 https://ir.csmu.edu.tw:8080/handle/310902500/23552
Relation:	JOURNAL OF MICROBIOLOGY IMMUNOLOGY AND INFECTION ,2021,v54,issue 5, P794-800
Appears in Collections:	[中山醫學大學研究成果] 期刊論文

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