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    Please use this identifier to cite or link to this item: https://ir.csmu.edu.tw:8080/ir/handle/310902500/23490


    Title: Discriminating Reflux from Non-Reflux Diseases of Superficial Veins in Legs by Novel Non-Contrast MR with QFlow Technique
    Authors: Tseng, YH;Chen, CW;Wong, MY;Yang, TY;Lin, BS;Ting, H;Huang, YK
    Keywords: MRI;non-contrast;venography;TRANCE;QFlow
    Date: 2021
    Issue Date: 2022-08-05T09:38:07Z (UTC)
    Publisher: MDPI
    Abstract: Objectives: To find an objective diagnostic tool for the superficial veins in legs. Methods: This study included 137 patients who underwent TRANCE-MRI from 2017 to 2020 (IRB: 202001570B0). Among them, 53 with unilateral leg venous diseases underwent a QFlow scan and were classified into the reflux and non-reflux groups according to the status of the great saphenous veins. Results: The QFlow, namely stroke volume (SV), forward flow volume (FFV), mean flux (MF), stroke distance (SD), and mean velocity (MV) measured in the external iliac, femoral, popliteal, and great saphenous vein (GSV). The SV, FFV, SD, MF, SD, and MV in the GSV (morbid/non-morbid limbs) demonstrated a favorable ability to discriminate reflux from non-reflux in the ROC curve. The SD in the GSV and GSV/PV ratio (p = 0.049 and 0.047/cutoff = 86 and 117.1) and the MV in the EIV/FV ratio, GSV, and GSV/PV ratio (p = 0.035, 0.034, and 0.025/cutoff = 100.9, 86.1, and 122.9) exhibited the ability to discriminate between reflux and non-reflux group. The SD, MV, and FFV have better ability to discriminate a reflux from non-reflux group than the SV and MF. Conclusions: QFlow may be used to verify the reflux of superficial veins in the legs. An increasing GSV/PV ratio is a hallmark of reflux of superficial veins in the legs.
    URI: http://dx.doi.org/10.3390/jpm11040242
    https://www.webofscience.com/wos/woscc/full-record/WOS:000643099700001
    https://ir.csmu.edu.tw:8080/handle/310902500/23490
    Relation: JOURNAL OF PERSONALIZED MEDICINE ,2021,v11,issue 4
    Appears in Collections:[中山醫學大學研究成果] 期刊論文

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