Perinatal Factors in Newborn Are Insidious Risk Factors for Childhood Autism Spectrum Disorders: A Population-based Study

doi:10.1007/s10803-021-04921-0

中山醫學大學機構典藏 CSMUIR > 中山醫學大學研究成果 > 期刊論文 > Item 310902500/23279

Please use this identifier to cite or link to this item: https://ir.csmu.edu.tw:8080/ir/handle/310902500/23279

Title:	Perinatal Factors in Newborn Are Insidious Risk Factors for Childhood Autism Spectrum Disorders: A Population-based Study
Authors:	Lee, IC;Wang, YH;Chiou, JY;Wei, JCC
Keywords:	Autism;Craniofacial anomalies;Neonatal jaundice;Hypoglycemia;Intrauterine growth retardation
Date:	2021
Issue Date:	2022-08-05T09:34:42Z (UTC)
Publisher:	SPRINGER/PLENUM PUBLISHERS
ISSN:	0162-3257
Abstract:	We analyzed claims data from the Taiwan National Health Insurance database, which contains data of 23.5 million Taiwan residents. We included children born after January 1, 2000 who had received a diagnosis of autism spectrum disorders (ASD). Patients who were not diagnosed with ASD were included in the control group. The ASD prevalence was 517 in 62,051 (0.83%) children. Neonatal jaundice, hypoglycemia, intrauterine growth retardation (IUGR), and craniofacial anomalies (CFA) differed significantly between the ASD and control groups. After logistic regressive analysis, the adjusted odds ratios of IUGR, CFA, neonatal hypoglycemia, and neonatal jaundice were 8.58, 7.37, 3.83, and 1.32, respectively. Those insidiously perinatal risk factors, namely CFA, IUGR, neonatal hypoglycemia, and neonatal jaundice, could increase the risk of ASD.
URI:	http://dx.doi.org/10.1007/s10803-021-04921-0 https://www.webofscience.com/wos/woscc/full-record/WOS:000621262200001 https://ir.csmu.edu.tw:8080/handle/310902500/23279
Relation:	JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS ,2022,v52,issue 1, P52-60
Appears in Collections:	[中山醫學大學研究成果] 期刊論文

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