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Please use this identifier to cite or link to this item:
https://ir.csmu.edu.tw:8080/ir/handle/310902500/21042
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Title: | Potentially Inappropriate Prescribing in Disabled Older Patients with Chronic Diseases: A Screening Tool of Older Persons' Potentially Inappropriate Prescriptions versus Beers 2012 Criteria |
Authors: | Yang, Po-Jen Lee, Yuan-Ti Tzeng, Shu-Ling Lee, Huei-Chao Tsai, Chin-Feng Chen, Chun-Chieh Chen, Shiuan-Chih Lee, Meng-Chih |
Contributors: | 醫學研究所 |
Keywords: | Disabled persons · Chronic disease · Older people · Risk factors · Inappropriate prescription · Polypharmacy |
Date: | 2015-08-01 |
Issue Date: | 2020-08-10T07:24:12Z (UTC)
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Publisher: | Med Princ Pract |
Abstract: | Abstract
Objective: To evaluate the prescription of potentially inappropriate medications (PIM), using the Screening Tool
of Older Persons’ potentially inappropriate Prescriptions
(STOPP) and Beers criteria, to disabled older people. Subjects and Methods: One hundred and forty-one patients
aged ≥ 65 years with Barthel scale scores ≤ 60 and a regular
intake of medication for chronic diseases at Chung Shan
Medical University Hospital from July to December 2012
were included, and their medical records were reviewed.
Comprehensive patient information was extracted from the
patients’ medical notes. The STOPP and Beers 2012 criteria
were used separately to identify PIM, and logistic regression
analyses were performed to identify risk factors for PIM. The
optimal cutoff for the number of medications prescribed for
predicting PIM was estimated using the Youden index. Results: Of the 141 patients, 94 (66.7%) and 94 (66.7%) had at
least one PIM identified by the STOPP and Beers criteria, respectively. In multivariate analysis, PIM identified by the Beers criteria were associated with the prescription of multiple medications (p = 0.013) and the presence of psychiatric
diseases (p < 0.001), whereas PIM identified by the STOPP
criteria were only associated with the prescription of multiple medications (p = 0.008). The optimal cutoff for the number of medications prescribed for predicting PIM by using
the STOPP or Beers criteria was 6. After adjustment for covariates, patients prescribed ≥ 6 medications had a significantly higher risk of PIM, identified using the STOPP or Beers
criteria, compared to patients prescribed <6 medications
(both p < 0.05). Conclusion: This study revealed a high frequency of PIM in disabled older patients with chronic diseases, particularly those prescribed ≥ 6 medications. |
URI: | https://ir.csmu.edu.tw:8080/ir/handle/310902500/21042 |
Relation: | Med Princ Pract 2015;24:565–570 |
Appears in Collections: | [醫學研究所] 期刊論文
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