Optical Coherence Tomography Angiography for Diagnosis of Choroidal Neovascularization in Chronic Central Serous Chorioretinopathy after Photodynamic Therapy

doi:10.1038/s41598-019-45080-8

中山醫學大學機構典藏 CSMUIR > 醫學科技學院 > 視光學系暨碩士班 > 期刊論文 > Item 310902500/20461

Please use this identifier to cite or link to this item: https://ir.csmu.edu.tw:8080/ir/handle/310902500/20461

Title:	Optical Coherence Tomography Angiography for Diagnosis of Choroidal Neovascularization in Chronic Central Serous Chorioretinopathy after Photodynamic Therapy
Authors:	Wu, J.-S. Chen, S.-N.
Contributors:	中山醫學大學視光學系
Keywords:	Central Serous Chorioretinopathy;Eye;Chorioretinopathy CSCR
Date:	2019-12
Issue Date:	2019-11-21T03:05:45Z (UTC)
Publisher:	Scientific Reports
ISSN:	2045-2322
Abstract:	The authors evaluated the proportion of choroidal neovascularization (CNV) detected by spectral-domain optical coherence tomography angiography (OCTA) in eyes with chronic central serous chorioretinopathy (CSC) (more than 3 months) with previous treatment via half-dose photodynamic therapy (PDT). All patients were followed up with at least twelve months. Macular angiograms were obtained using spectral-domain OCT (SD-OCT, RTVue XR; Optovue). CNV was defined as flow in the outer retinal slab between the outer plexiform layer and Bruch’s membrane. Clinical characteristics were compared between CNV and non-CNV groups. Seventy eyes of 61 patients (51 male and 10 female) were included. The average age was 46.2 years old. The average duration of symptom was 32.9 months. All patients were treated with half-dose PDT initially. Eleven eyes (15.7%) received more than one session of PDT. CNV was diagnosed in 32 of 70 eyes (45.7%) based on OCTA. Only 6 of the 32 eyes (18.8%) needed intravitreal anti- vascular endothelial growth factor (VEGF) therapy for the exudative activity of CNV. Older age (p = 0.059), larger PDT spot size (p = 0.024), and thinner subfoveal choroidal thickness (p = 0.008) were noted in CNV group. The authors conclude that OCTA reveals high rates of CNV associated with chronic CSC after PDT. Patients in the CNV group had older age, larger PDT spot size, and thinner subfoveal choroidal thickness. OCTA may be considered as a first step in identifying CNV in chronic CSC following PDT. © 2019, The Author(s).
URI:	https://ir.csmu.edu.tw:8080/ir/handle/310902500/20461
Relation:	Scientific Reports, Volume 9, Issue 1, NO. 9040
Appears in Collections:	[視光學系暨碩士班] 期刊論文

Files in This Item:

File	Description	Size	Format
Optical-Coherence-Tomography-Angiography-for-Diagnosis-of-Choroidal-Neovascularization-in-Chronic-Central-Serous-Chorioretinopathy-after-Photodynamic-Therapy2019Scientific-Reports.pdf		1352Kb	Adobe PDF	140	View/Open

View Licence

Loading...