目的：巴東體屬感染症為近十年來才被國際認知的重要新興人畜共通傳染病(emerging anthropozoonoses)，因此台灣地區急待開發此傳染病研究領域與瞭解此傳染病於國內現況。巴東體屬感染症中最著名且被了解較為清楚的包括由Bartonella bacilliformis引起的卡利盎氏病，B quintana引起的戰壕熱，及B. henselae引起的貓抓熱。本研究的目的欲以血清學篩檢法；針對本省中部地區包括彰化、雲林及台中市傳統市場流浪貓和家貓，進行貓抓熱病原感染流行病學調查。方法：初步流行病學研究調查發現，以便利取樣方式採集之50隻貓全血樣本中，以B. henselae為抗原製備之間接免疫螢光分析玻片加以測定。結果：貓血清抗體陽性率為60% (30/50)，以巧克力固體培養基為基底進行之全血培養，結果顯示貓菌血症盛行率為22% (11/50)。分離出之巴東體屬細菌株進一步之分子生物學分析與菌種定序鑑定，初步顯示皆為B. henselae。感染之重要危險因子初步顯示為包括小於一歲之幼貓、跳蚤寄生、與流浪貓等。結論：顯示本省中部地區貓族群中的確攜帶有此重要之新興人畜共通傳染病原。政府相關單位應加以宣導重視此傳染病可能對台灣地區居民健康之威脅，未來並需更深入執行大規模之流行病學調查。
Purpose: In the past ten years, Bartonellosis was recognized as a kind of important diseases, called emerging anthropozoonoses, through the world. Hence the aim of this study is to study and understand the condition of emerging infectious disease in Taiwan. Recently, some studies have identified the pathogens of these infectious diseases which were associated with Bartonella spp., such as B. bacilliformis induced Carrion's disease, B. quintana induced trench fever and B. henselae induced cat-scratch fever. Method: In this study fifty blood samples collected from stray cats which were caught in the traditional market located in Taichung, Yunlin and Changhua for epidemiological investigation. These samples were detected by indirect fluorescent method for positive reaction and chocolate-based incubation for bacteremia. Results: The results indicated the prevalence of positive reaction was 60% (30/50) and the prevalence of bacteremia was 22% (11/50). In addition, B. henselae was identified in these infectious cases and there were positive correlation between young kitten, cat-flea infestation, and stray cats. Conclusion: In Taiwan at least in central area of Taiwan we identified B. henselae in stray cats and may become an important zoonotic infectious disease in the future in Taiwan. Hence we strongly suggested a massive investigation about this emerging infectious disease is needed in the near future.
