中山醫學大學機構典藏 CSMUIR:Item 310902500/19049
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    题名: Economic cost and burden of dengue during epidemics and non-epidemic years in Taiwan
    作者: DL, Luh
    CC, Liu
    YR, Luo
    SC, Chen
    贡献者: 中山醫學大學
    关键词: Dengue;Disability-adjusted life years (DALYs);Disease burden;Economic cost of disease;Epidemic
    日期: 2018-03
    上传时间: 2018-03-27T08:58:09Z (UTC)
    出版者: Elsevier Ltd
    ISSN: 18760341
    摘要: Background: Determining the disease and economic burden of dengue is critical for the allocation of public health resources. Several studies have used disability-adjusted life-years (DALYs) to estimate the disease burden of dengue in different regions. However, there are no published studies discussing the estimates of dengue-related economic and disease burden specifically in Taiwan. Objectives: We assessed the economic cost and disease burden of dengue infections in Taiwan for the period 1998–2014, and compared these during epidemic and non-epidemic years. Methods: We estimated the annual DALYs per million population using the disability weights for dengue fever (DF), dengue hemorrhagic fever (DHF), dengue shock syndrome (DSS), and death cases. Economic costs were estimated and divided into direct (medical costs) and indirect costs (lost work days and caregiver fees). Results: For the period 1998–2014, a mean of 115.3 (range: 6.3–934.3) DALYs per million population annually were lost to dengue. In epidemic years, direct costs associated with dengue resulted mostly from hospitalization (86.09%), emergency (7.77%), outpatient (6.10%), and drug costs (0.03%). For indirect costs, lost productivity due to death (70.76%) was the dominant contributor. Overall, the costs were 12.3 times higher in epidemic years than in non-epidemic years (Wilcoxon rank sum test, p < 0.05). Conclusions: This study is the first to evaluate the economic costs and disease burden of dengue infections for this period in Taiwan, and reveals significant differences in economic impact between epidemic and non-epidemic years. © 2017
    URI: https://www.doi.org/10.1016/j.jiph.2017.07.021
    https://ir.csmu.edu.tw:8080/ir/handle/310902500/19049
    關聯: Journal of Infection and Public Health Volume 11, Issue 2, March 2018, Pages 215-223
    显示于类别:[公共衛生學系暨碩士班] 期刊論文

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