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Please use this identifier to cite or link to this item:
https://ir.csmu.edu.tw:8080/ir/handle/310902500/18567
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Title: | Ten-Year Registry of Native Kidney Biopsy from a Single Center in Taichung |
Authors: | Hsiao, Kuang-Chin Lian, Jong-Da Wu, Shen-Wen Hung, Tung-Wei Lin, Chih-Kuang Wen, Mei-Chin Chang, Horng-Rong |
Contributors: | 中山醫大 |
Keywords: | native renal biopsy;nephrotic syndrome;membranous nephropathy |
Date: | 2012 |
Issue Date: | 2017-11-14T08:29:16Z (UTC)
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Abstract: | BACKGROUND: Renal biopsy plays an important role in diagnosis of renal disease, especially in
nephrotic syndrome. IgA nephropathy had been the most common glomerular disease in the whole
world. However, there were not many reports about the epidemiological incidence and causes of renal
disease in Taiwan.
METHODS: We performed a single-center, retrospective analysis of patients with renal disease
that was documented by precutaneous renal biopsy from October 2000 to December 2010. Demographic
data (age, gender), laboratory investigations such as serum urea, serum creatinine, proteinuria,
haematuria, 24-hour urinary protein, and creatinine clearance, and clinical diagnosis were collected for
analysis.
RESULTS: There were 444 native kidney biopsies performed, 238 males (53.6%) and 206 females
(46.7%). The average age of patients was 47.6 years. The most common clinical presentation as an
indication for renal biopsy was nephrotic syndrome (52%). Membranous nephropathy (17.5%) was the
most common glomerular disease and the most frequent cause (29.8%) of nephrotic syndrome. Primary
glomerular disease accounted for 55% of all biopsies and membranous nephropathy was the most
frequent cause (31.7%) of the primary glomerular disease. Lupus nephritis was the most frequent
secondary glomeurlonephritis (53.21%).
CONCLUSIONS: Instead of IgA nephropathy, membranous nephropathy was the most common
primary glomerular disease and lupus nephritis was the most common secondary glomerulonephritis in
our analysis. The high prevalence of membranous nephropathy could be due to older age and higher
incidence of patients with nephrotic syndrome in our database. |
URI: | http://dx.doi.org/10.6221/AN.2011022 https://ir.csmu.edu.tw:8080/ir/handle/310902500/18567 |
Relation: | Acta Nephrologica 26(2): 68-73, 2012 |
Appears in Collections: | [醫學研究所] 期刊論文
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