Cytotoxic evaluation of root canal filling materials on primary human oral fibroblast cultures and a permanent hamster cell line I

中山醫學大學機構典藏 CSMUIR > 口腔醫學院 > 牙醫學系暨碩士班 > 期刊論文 > Item 310902500/18396

Please use this identifier to cite or link to this item: https://ir.csmu.edu.tw:8080/ir/handle/310902500/18396

Title:	Cytotoxic evaluation of root canal filling materials on primary human oral fibroblast cultures and a permanent hamster cell line I
Authors:	Chang, Y.-C.
Date:	2001
Issue Date:	2017-08-14T08:50:52Z (UTC)
ISSN:	0099-2399
Abstract:	To date there has been very little data on the cytotoxic response of different cell lines to root canal sealers. The objective of this study was to determine the cytocompatibility of three different extracts of root canal sealers and to compare the cytotoxic response of these materials on two different primary human oral fibroblasts (derived from gingiva and buccal mucosa) and one permanent hamster cell line (V79 cells). Cytotoxicity was judged using an assay of tetrazolium bromide reduction. The results showed that root canal sealers (AH plus, Canals, and N2) were cytotoxic to primary human oral fibroblast cultures and V79 cells. It was found that N2 was the most toxic root canal sealer among those tested in all cultures. The toxicity decreased in an order of N2 > AH plus ≒ Canals. The sensitivity of toxicity depended on the materials tested and the cell culture system used. Copyright © 2001 by The American Association of Endodontists.
URI:	http://dx.doi.org/ https://www.scopus.com/inward/record.uri?eid=2-s2.0-0035462664&partnerID=40&md5=cfdee7adea1fdb619910b8137aff03bc https://ir.csmu.edu.tw:8080/ir/handle/310902500/18396
Relation:	Journal of Endodontics 27 (9) ,571-573
Appears in Collections:	[牙醫學系暨碩士班] 期刊論文

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