Cytotoxicity of resin-based restorative materials on human pulp cell cultures

doi:10.1067/moe.2002.126341

中山醫學大學機構典藏 CSMUIR > 口腔醫學院 > 牙醫學系暨碩士班 > 期刊論文 > Item 310902500/18384

Please use this identifier to cite or link to this item: https://ir.csmu.edu.tw:8080/ir/handle/310902500/18384

Title:	Cytotoxicity of resin-based restorative materials on human pulp cell cultures
Authors:	Huang, F.-M.;Chang, Y.-C.
Date:	2002
Issue Date:	2017-08-14T08:50:02Z (UTC)
ISSN:	1079-2104
Abstract:	Objective. The objective of this study was to determine the cytocompatibility of 5 different extracts of resin-based restorative materials (2 resin-modified glass ionomer cements, 1 compomer, and 2 composite resins) on human pulp cells. Study design. Set specimens from 2 resin-modified glass-ionomer cements (Fuju II LC and Fuji IX), 1 compomer (Dyract), and 2 composite resins (Tetric and Superfil) were eluted with culture medium for 2 and 5 days. The effects of resin-based restorative materials on human pulp cells were evaluated with cytotoxicity and mitochondrial activity assays. Results. The results showed that the eluates from resin-modified glass-ionomer, compomer, and composite resins were cytotoxic to primary human pulp cells. In addition, Superfil, Fuji IX, and Tetric demonstrated an inhibitory effect on mitochondrial activity of human pulp cells. It was found that composite resin Superfil was the most toxic restorative material among the chemicals tested. Conclusion. The influence of the cytotoxicity depended on the materials tested. Compomer or light-curing resin-modified glass ionomer may initially react more favorably to pulp cells. © 2002, Mosby, Inc.
URI:	http://dx.doi.org/10.1067/moe.2002.126341 https://www.scopus.com/inward/record.uri?eid=2-s2.0-0036717674&doi=10.1067%2fmoe.2002.126341&partnerID=40&md5=6af29eac148bb2a5bca8365bee2e51b4 https://ir.csmu.edu.tw:8080/ir/handle/310902500/18384
Relation:	Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics 94 (3) ,361-365
Appears in Collections:	[牙醫學系暨碩士班] 期刊論文

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