The biocompatibility evaluation of epoxy resin-based root canal sealers in vitro

doi:10.1016/S0142-9612(01)00081-3

中山醫學大學機構典藏 CSMUIR > 口腔醫學院 > 牙醫學系暨碩士班 > 期刊論文 > Item 310902500/18288

jsp.display-item.identifier=請使用永久網址來引用或連結此文件: https://ir.csmu.edu.tw:8080/ir/handle/310902500/18288

题名:	The biocompatibility evaluation of epoxy resin-based root canal sealers in vitro
作者:	Huang, T.-H.;Yang, J.-J.;Li, H.;Kao, C.-T.
关键词:	Alkaline single cell gel electrophoresis;Biocompatibility of epoxy resin sealer;MTT assay
日期:	2002
上传时间:	2017-08-09T04:44:58Z (UTC)
ISSN:	1429612
摘要:	The cytotoxic and mutagenic effects of epoxy resin-based root canal sealer AH26 and AH-Plus were determined in vitro. Root canal sealers were eluted for 24h in dimethyl sulfoxide (DMSO) and diluted in culture medium. Cytotoxic effects were assessed using the MTT [tetrazolium dye, 3-(4.5-dimethylthiazol-2-yl)-2.5-diphenyltetrazolium bromide, C18H16N5SBr] assay for mitochondrial enzyme activity and also the cell viability. Genotoxicity assays were assessed using the alkaline single cell gel electrophoresis assay (comet assay) for DNA damage measurement. Result indicated that both the AH26 and AH-Plus sealers exhibited a dose-dependent increase in astrocyte toxic effects. Additionally, dose-dependent astrocyte DNA damage was also noted for both sealers. Therefore, these epoxy resin-based sealers, AH26 and AH-Plus demonstrated both cytotoxicity and genotoxicity in vitro. Copyright © 2001 Elsevier Science Ltd.
URI:	http://dx.doi.org/10.1016/S0142-9612(01)00081-3 https://www.scopus.com/inward/record.uri?eid=2-s2.0-0036027554&doi=10.1016%2fS0142-9612%2801%2900081-3&partnerID=40&md5=f8e5b68987f669484cce9e48f397b914 https://ir.csmu.edu.tw:8080/ir/handle/310902500/18288
關聯:	Biomaterials 23(1) ,77-83
显示于类别:	[牙醫學系暨碩士班] 期刊論文

文件中的档案:

没有与此文件相关的档案.

在CSMUIR中所有的数据项都受到原著作权保护.

TAIR相关文章

数据加载中.....