Clinical Outcomes and Prognostic Factors of Cancer Patients with Pyogenic Liver Abscess

doi:10.1007/s11605-011-1650-3

中山醫學大學機構典藏 CSMUIR > 醫學院 > 醫學系 > 期刊論文 > Item 310902500/17877

Please use this identifier to cite or link to this item: https://ir.csmu.edu.tw:8080/ir/handle/310902500/17877

Title:	Clinical Outcomes and Prognostic Factors of Cancer Patients with Pyogenic Liver Abscess
Authors:	Chen, Shiuan-Chih Lee, Yuan-Ti Tsai, Shih-Jei Lai, Kuang-Chi Huang, Chi-Chou Wang, Po-Hui Chen, Chun-Chieh Lee, Meng-Chih
Contributors:	中山醫學大學
Keywords:	Pyogenic liver abscess;Risk factor;Mortality;Neoplasm
Date:	2011
Issue Date:	2017-06-29T09:28:29Z (UTC)
Publisher:	Journal of Gastrointestinal Surgery
ISSN:	1091-255X
Abstract:	Abstract Purpose Pyogenic liver abscess (PLA) of cancer patients often has a poor prognosis, but corresponding prognostic factors are less investigated. This study aimed to identify predictors of mortality in cancer patients with PLA. Patients and Methods Medical records of 85 consecutive cancer patients (46 with hepatobiliary pancreatic cancer, 14 with gastrointestinal cancer, and 25 with non-digestive system cancer) having PLA who were admitted to two university hospitals were retrospectively reviewed. The predictors of mortality were determined using Cox regression model. Results The overall case fatality rate was 33%. In multivariate analysis, the greater Acute Physiology and Chronic Health Evaluation II score (P = 0.028), multiloculated abscess (P = 0.025), and polymicrobial infection (P = 0.003) were associated with mortality. In subgroup analysis of the 25 patients with multiloculated abscess undergoing percutaneous catheter drainage as primary treatment, the case fatality rates of patients with a solitary smaller abscess (size < 5 cm), those with a solitary larger abscess (size > 5 cm), and those with larger multiple abscesses were 0%, 36%, and 85%, respectively (P = 0.002; using χ2 for trend). Conclusions The advanced disease stage, multiloculated abscess, and polymicrobial infection posed a greater mortality risk in cancer patients with PLA. Moreover, an early surgical approach should be considered for cancer patients having large, multiloculated complex PLAs.
URI:	http://dx.doi.org/10.1007/s11605-011-1650-3 https://ir.csmu.edu.tw:8080/ir/handle/310902500/17877
Relation:	Journal of Gastrointestinal Surgery November 2011, 15:2036
Appears in Collections:	[醫學系] 期刊論文

Files in This Item:

File	Description	Size	Format
index.html		0Kb	HTML	220	View/Open

View Licence

Loading...