In vitro properties of gellan gum sponge as the dental filling to maintain alveolar space

doi:10.1016/j.carbpol.2012.01.017

中山醫學大學機構典藏 CSMUIR > 醫學科技學院 > 醫學檢驗暨生物技術學系暨碩士班 > 期刊論文 > Item 310902500/15947

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题名:	In vitro properties of gellan gum sponge as the dental filling to maintain alveolar space
作者:	Chang, Shwu Jen Huang, Yi-Ting Yang, Shun-Chun Kuo, Shyh-Ming Lee, Ming-Wei
贡献者:	中山醫學大學
关键词:	Dental filling;Gellan gum;Teruplug®
日期:	2012
上传时间:	2016-09-06T07:34:16Z (UTC)
ISSN:	0144-8617
摘要:	The insertion of dental filling into the dental cavity is a common method of maintaining the space and shape of dental cavities after dental extractions. To develop novel dental fillings meeting clinical requirements, gellan gum (GG) is selected in this study to prepare fillings with specific characteristics by modulating gellan gum concentrations (denoted as GG-DF). The results indicate that the microstructure, porosity, and compression modulus of 1.5% and 1.75% GG-DF are similar to a commercially product (Teruplug®) and with good blood absorption capacity. The degradation ratio of Teruplug® in an amylase/phosphate buffer solution after 4 weeks is 80% whereas that of 1.5% and 1.75% GG-DF is 65%. Cell migration studies confirmed that the migration ability of fibroblast was significantly inhibited by gellan gum. These results demonstrate that 1.5% and 1.75% GG-DF are potentially viable for developing into dental fillings.
URI:	http://dx.doi.org/10.1016/j.carbpol.2012.01.017 https://ir.csmu.edu.tw:8080/ir/handle/310902500/15947
關聯:	Carbohydrate Polymers Volume 88, Issue 2, 2 April 2012, Pages 684–689
显示于类别:	[醫學檢驗暨生物技術學系暨碩士班] 期刊論文

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