ADSC therapy in neurodegenerative disorders

doi:10.3727/096368914X678445

中山醫學大學機構典藏 CSMUIR > 醫學科技學院 > 醫學檢驗暨生物技術學系暨碩士班 > 期刊論文 > Item 310902500/15897

Please use this identifier to cite or link to this item: https://ir.csmu.edu.tw:8080/ir/handle/310902500/15897

Title:	ADSC therapy in neurodegenerative disorders
Authors:	TM, Chan JY, Chen LI, Ho HP, Lin KW, Hsueh DD, Liu YH, Chen AC, Hsieh NM, Tsai DY, Hueng ST, Tsai PW, Chou SZ, Lin HJ, Harn
Contributors:	中山醫學大學
Date:	2016
Issue Date:	2016-09-05T07:14:29Z (UTC)
Publisher:	Cognizant Communication Corporation
ISSN:	0963-6897
Abstract:	Neurodegenerative disorders, chronic diseases that can severely affect the patient's daily life, include amyotrophic lateral sclerosis, Parkinson's, Alzheimer's, and Huntington's diseases. However, these diseases all have the common characteristic that they are due to degenerative irreversibility, and thus no efficient drugs or therapy methods can mitigate symptoms completely. Stem cell therapy, such as adipose tissue-derived stem cells (ADSCs), is a promising treatment for incurable disorders. In this review, we summarized the previous studies using ADSCs to treat neurodegenerative disorders, as well as their therapeutic mechanisms. We also suggested possible expectations for future human clinical trials involving minimized intracerebroventricular combined with intravenous administration, using different cell lineages to finish complementary therapy as well as change the extracellular matrix to create a homing niche. Depending on successful experiments in relevant neurodegenerative disorders models, this could form the theoretical basis for future human clinical trials.
URI:	http://dx.doi.org/10.3727/096368914X678445 https://ir.csmu.edu.tw:8080/ir/handle/310902500/15897
Relation:	Cell Transplant. 2014;23(4-5):549-57
Appears in Collections:	[醫學檢驗暨生物技術學系暨碩士班] 期刊論文

Files in This Item:

File	Description	Size	Format
index.html		0Kb	HTML	617	View/Open

View Licence

Loading...