中山醫學大學機構典藏 CSMUIR:Item 310902500/12002
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    請使用永久網址來引用或連結此文件: https://ir.csmu.edu.tw:8080/ir/handle/310902500/12002


    題名: Use of seasonal influenza virus titer and respiratory symptom score to estimate effective human contact rates.
    作者: Chen SC;You SH;Ling MP;Chio CP;Liao CM.
    貢獻者: 中山醫學大學
    關鍵詞: influenza;behavior;contact rate;symptom score;modeling
    日期: 2012
    上傳時間: 2015-08-07T10:00:42Z (UTC)
    摘要: BACKGROUND:
    We linked viral titers and respiratory symptom scores for seasonal influenza to estimate the effective contact rate among schoolchildren.
    METHODS:
    We analyzed 274 diary-based questionnaires. In addition, 2 sets of influenza data from published studies were used to investigate the relationship between viral titer, total symptom score, and normalized contact rate in children.
    RESULTS:
    The mean number (SD) of contacts for children in grades 7 to 9 ranged from 9.44 ± 8.68 to 11.18 ± 7.98 person⁻¹ day⁻¹; contact behavior was similar across school grades. The mean number of contacts was 5.66 ± 6.23 person⁻¹ day⁻¹ (range, 0 to 44 person⁻¹ day⁻¹) for the age group of 13 to 19 years. Estimated contact age, household size, contact duration, and contact frequency were the variables most strongly associated with total number of contacts. We also found that a reduction in total respiratory symptom scores among infected individuals had a positive correlation with an increase in the normalized contact rate.
    CONCLUSIONS:
    The relationship between daily virus titer and respiratory symptom score can be used to estimate the effective contact rate in explaining the spread of an airborne transmissible disease. The present findings can be incorporated into population-dynamic models of influenza transmission among schoolchildren.
    URI: https://ir.csmu.edu.tw:8080/ir/handle/310902500/12002
    關聯: J Epidemiol. 2012;22(4):353-63.
    顯示於類別:[公共衛生學系暨碩士班] 期刊論文

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