本實驗利用水熱法將銳鈦型態的二氧化鈦粉末在10M NaOH 中在110℃下反應4天合成出具有多層次結構的鈦酸鈉奈米管(Na2Ti3O7)，簡稱NaTNTs。再利用離子交換法先將Na+離子交換NH4+離子，之後使用MnNO3以不同濃度以及鍛燒溫度條件交換錳金屬離子合成出Mn-doped TiO2奈米管的光觸媒。樣品利用SEM及XRD分別鑑定表面型態以及晶相結構，BET測定樣品的表面積以及孔徑大小，錳金屬元素分析利用中子活化測定MnTNTs所含錳的含量，DRS測定MnTNTs的可見光以及紫外光的吸收。為了測試觸媒的光催化活性，利用400W高壓汞燈測定觸媒對紫外光以及可見光進行對亞甲基藍的降解反應，MB光催化降解活性為800℃> 600℃> 700℃> 500℃> 400℃> 110℃。奈米材料的表面效應與小尺寸效應，會造成物質於物理或化學上性質的改變，而奈米顆粒之毒性除了與前述相關外，也與本身材質特性相關，但是何者為重要，還不甚清楚，為了更瞭解以及預防此奈米材料所可能帶來的種種危害，在進一步對THP-1人類單核球細胞做發炎反應的探討，在未以LPS誘發的THP-1發炎反應狀況下，有附載以及未附載錳金屬鈦酸銨奈米管均對細胞激素而言是有影響的。
In this study,multi-walled sodium titanate nanotubes(Na2Ti3O7,abbreviated as NaTNTs) were prepared by hydrothermal treating Titanium Dioxide anatase powder in 10M NaOH at 110℃ for 4 days. First Na ion was changed NH4 ion in ion exchange, after Mn-doped TiO2nanotubes was prepared to form ion exchange in different MnNO3 aqueous concentration, MnTNTs was calcined at different temperature.The morphology and crystalline structures of the samples were characterized by SEM and XRD. Specific surface area and pore volume of the MnTNTs were characterized by BET. Element analysis of the MnTNTs was characterized by neutron activation analysis. Visible region and UV region absorption was used DRS. Photocatalytic degradation of methylene blue (MB) experiments was utilized 400W high pressure Mercury lamp. Identification of Visible and UV absorption,MB degradation activity followed the order 800℃>600℃>700℃>500℃>400℃>110℃. Nanoparticle’s surface and small-dimension effects will cause physical or chemical changes of the material. Initialnanotubes were converted to anatase nanowires after the calcination at 400℃. The calcination at higher temperatures led to gradual decomposition of the wires to rods.Moreover, beside the toxicity of the nanoparticles related to above description,inflammation associated cytokines were evaluatedon THP-1 human monocytes cell line in this study. Different titanate nanoparticals with or withoutLPS-induced cytokines excretion from THP-1cell were compared, to elucidate the material characteristics related effect on inflammation.
