中山醫學大學機構典藏 CSMUIR:Item 310902500/4014
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    jsp.display-item.identifier=請使用永久網址來引用或連結此文件: https://ir.csmu.edu.tw:8080/ir/handle/310902500/4014


    题名: 胞漿素原活化劑及胞漿素系統在子宮頸上皮內贅瘤及子宮頸癌的表現
    Plasminogen Activator and Plasmin System Expression in Cervical Intraepithelial Neoplasia and Cervical Cancer
    作者: 鄭義銅;楊順發;王博輝
    贡献者: 中山醫學大學:醫學系
    日期: 2011
    上传时间: 2011-07-01T04:20:11Z (UTC)
    摘要: Backgrounds: To investigate the association of stromal cell-derived factor-1
    (SDF-1) gene polymorphisms with the neoplastic lesions of uterine cervix in
    Mid-Taiwan women. Methods: 498 blood samples were collected from 161 patients
    with neoplasia of uterine cervix, including 76 cancer patients and 61 patients with
    high-grade dysplasia, 24 low-grade dysplasia, and 337 normal women. Stromal
    cell-derived factor-1 (SDF-1) gene was selected. Results: Compared with
    homozygotes GG, we found the heterozygote genotype, GA has no significantly
    different distribution between patients with cervical neoplasia and normal women (P
    = 0.539). Moreover, compared with cancer patients and patients with high-grade
    dysplasia and low--grade dysplasia, women with GG also have no significantly
    different distribution. Conclusions: SDF-1 A gene polymorphism could be not
    considered as a factor related to an increased susceptibility of neoplasia of uterine
    cervix.
    URI: https://ir.csmu.edu.tw:8080/ir/handle/310902500/4014
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