中山醫學大學機構典藏 CSMUIR:Item 310902500/3499
English  |  正體中文  |  简体中文  |  全文笔数/总笔数 : 17918/22933 (78%)
造访人次 : 7436186      在线人数 : 59
RC Version 7.0 © Powered By DSPACE, MIT. Enhanced by NTU Library IR team.
搜寻范围 查询小技巧：
  • 您可在西文检索词汇前后加上"双引号"，以获取较精准的检索结果
  • 若欲以作者姓名搜寻，建议至进阶搜寻限定作者字段，可获得较完整数据
    •  进阶搜寻


    jsp.display-item.identifier=請使用永久網址來引用或連結此文件: https://ir.csmu.edu.tw:8080/ir/handle/310902500/3499


    题名: Effects of electrical cervical spinal cord stimulation on cerebral blood perfusion, cerebrospinal fluid catecholamine levels, and oxidative stress in comatose patients
    作者: J. -T. Liu;W. -C. Tan;Wen-Jui Liao
    贡献者: 中山醫學大學：醫學系
    关键词: Catecholamines;cerebral blood perfusion;comatose patients;electrical spinal cord stimulation;oxidative stress
    日期: 2008
    上传时间: 2011-03-01T02:44:34Z (UTC)
    摘要: Objectives
    Electrical spinal cord stimulation (SCS) is used to treat of chronic pain, obstructive arterial-related ischemia, and anginal pain. This study investigated cerebral blood perfusion, cerebrospinal fluid (CSF) catecholamine levels, and oxidative stress before and after cervical SCS in comatose patients.
    Methods
    We evaluated cerebral blood perfusion, catecholamine (dopamine, norepinephrine, and epinephrine) levels, and oxidative stress in 20 comatose patients before and after SCS. After SCS for six months, cerebral blood perfusion (SPECT index, 2.293 ± 0.255 vs. 2.779 ± 0.209, p< 0.001), dopamine (49.0 ± 12.1 vs. 198.9 ± 62.6, p = 0.025), and norepinephrine (197.6 ± 62.9 vs. 379.6 ± 52.6, p = 0.021) but not epinephrine were significantly increased. Moreover, Superoxide free radicals in whole blood were significantly decreased (210,079 ± 47,763 vs. 109,212 ± 20,086, p = 0.011) after SCS. Nine patients recovered from the consciousness within 71–287 days.
    Conclusions
    Increase of cerebral blood perfusion and catecholamines (dopamine and norepinephrine) in CSF after SCS was observed, whereas epinephrine level was unchanged. The Superoxide free radicals were decreased after SCS. The results suggest that SCS increases cerebral blood perfusion, attenuates oxidative stress and increases biogenic amines in comatose patients.
    URI: https://ir.csmu.edu.tw:8080/handle/310902500/3499
    關聯: Acta Neurochirurgica Supplementum, 2008, Volume 101, Part 2, 71-76
    显示于类别:[醫學系] 期刊論文

    文件中的档案:

    档案 描述 大小格式浏览次数
    index.html0KbHTML216检视/开启


    SFX Query

    在CSMUIR中所有的数据项都受到原著作权保护.

    TAIR相关文章

    DSpace Software Copyright © 2002-2004  MIT &  Hewlett-Packard  /   Enhanced by   NTU Library IR team Copyright ©   - 回馈