中山醫學大學機構典藏 CSMUIR:Item 310902500/25043
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    题名: Hyaluronic Acid Injection Laryngoplasty for Unilateral Vocal Fold Paralysis-A Systematic Review and Meta-Analysis
    作者: Wang, CC;Wu, SH;Tu, YK;Lin, WJ;Liu, SA
    关键词: hyaluronic acid;injection laryngoplasty;unilateral vocal fold paralysis;meta-analysis
    日期: 2020
    上传时间: 2022-08-09T09:27:30Z (UTC)
    出版者: MDPI
    摘要: Unilateral vocal fold paralysis (UVFP) is a common disorder that may cause glottal closure insufficiency and then hoarseness of voice and aspiration during swallowing. We conducted a systematic review and meta-analysis to evaluate whether hyaluronic acid (HA) injection laryngoplasty (IL) is an effective treatment for patients with UVFP. Comprehensive systematic searches were undertaken using PubMed, EBSCO Medline, and Cochrane Library databases. We appraised the quality of studies according to preset inclusion and exclusion criteria. The lengths of follow-up were divided into short-term (3 months or shorter), medium-term (6 months), and long-term (12 months or longer). We performed random-effect meta-analysis to estimate the changes in voice-related quality of life, perceptual evaluation by grading systems, voice lab analysis of maximal phonation time, and normalized glottal gap area, before and after HA IL. Fourteen studies were eligible for the final analysis. The results showed that patients' glottal closure insufficiency could be improved; maximal phonation time could be prolonged; perceptual evaluations of the voice and quality of life were better after HA IL, but the duration of treatment effect varied among different studies. In conclusion, HA IL is an effective treatment for UVFP, which may achieve a long-term effect and therefore reduce the likelihood of requiring permanent medialization thyroplasty.
    URI: http://dx.doi.org/10.3390/cells9112417
    https://www.webofscience.com/wos/woscc/full-record/WOS:000592987800001
    https://ir.csmu.edu.tw:8080/handle/310902500/25043
    關聯: CELLS ,2020 ,v9 ,issue 11
    显示于类别:[中山醫學大學研究成果] 其他文獻

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