中山醫學大學機構典藏 CSMUIR:Item 310902500/24822
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    题名: Antiplatelet agents and anticoagulants increased the bleeding risk of bedside percutaneous dilational tracheostomy in critically ill patients
    作者: Huang, YH;Tseng, CH;Chan, MC;Lee, BJ;Lin, CH;Chang, GC
    关键词: Anticoagulants;Antiplatelet agents;Bleeding;Critically ill patients;Percutaneous dilational tracheostomy
    日期: 2020
    上传时间: 2022-08-09T08:08:33Z (UTC)
    出版者: ELSEVIER TAIWAN
    ISSN: 0929-6646
    摘要: Background: The main objective of this study was to investigate the safety of bedside percu- taneous dilational tracheostomy (PDT) by pulmonologists in critically ill patients, and the fac- tors associated with complications resulting from PDT. Methods: We retrospectively enrolled critically ill patients who had undergone bedside PDT in the intensive care units (ICUs) and respiratory care center from February 2016 to December 2018. Results: A total of 312 patients were included for analysis, with a mean age of 69.6 +/- 17.7 years. Two hundred and eight of the patients were male (66.7%). The mean acute physiology and chronic health evaluation II score was 25.3 +/- 6.3, and the mean body mass index was 22.4 +/- 4.2. Most of the patients were intubated due to respiratory disorders (51.3%). Fifty-six patients (17.9%) received antiplatelet agents or an anticoagulant regularly prior to PDT. All enrolled patients were undergone bedside PDT successfully. The total complication rate of PDT was 14.4%. Patients who took antiplatelet agents or anticoagulants regularly before PDT had a higher risk of bleeding than patients who went without (26.8% versus 7.0%, adjusted odds ratio 4.93 [95% f 2.16-11.25], p < 0.001). Finally, a longer length of intubation resulted in a higher probability in the length of ICU stay being S28 days (adjusted odds ratio 1.11 [95% CI 1.08-1.14], p < 0.001). Conclusion: Our study demonstrated that it was feasible for pulmonologists to perform bedside PDT in critically ill patients. However, antiplatelet agents and anticoagulants use increased the risk of bleeding in PDT patients. Copyright (C) 2019, Formosan Medical Association. Published by Elsevier Taiwan LLC. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/bync-nd/4.0/).
    URI: http://dx.doi.org/10.1016/j.jfma.2019.10.014
    https://www.webofscience.com/wos/woscc/full-record/WOS:000544894700008
    https://ir.csmu.edu.tw:8080/handle/310902500/24822
    關聯: JOURNAL OF THE FORMOSAN MEDICAL ASSOCIATION ,2020 ,v119 ,issue 7 ,p1193-1200
    显示于类别:[中山醫學大學研究成果] 期刊論文

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