中山醫學大學機構典藏 CSMUIR:Item 310902500/24774
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    题名: The Relationship Between Abdominal Body Composition and Metabolic Syndrome After a Weight Reduction Program in Adult Men with Obesity
    作者: Liao, CC;Sheu, WHH;Lin, SY;Lee, WJ;Lee, IT
    关键词: body mass index;intra-abdominal fat;magnetic resonance imaging;metabolic syndrome;subcutaneous abdominal fat;visceral fat
    日期: 2020
    上传时间: 2022-08-09T08:07:47Z (UTC)
    出版者: DOVE MEDICAL PRESS LTD
    ISSN: 1178-7007
    摘要: Purpose: To assess the relationship between changes in abdominal adipose tissue and metabolic syndrome (MetS) in men with obesity after a weight reduction program (WRP). Patients and Methods: Adult men with obesity and MetS were recruited for this prospective single-arm intervention study. Participants consumed an energy-restricted diet of 1200 kcal/day and performed 50-mins aerobic exercise daily for 12 weeks. Changes in the components of MetS were recorded. Changes in subcutaneous abdominal fat area (SAFA) and intra-abdominal fat area (IAFA) at the umbilicus level were determined using magnetic resonance imaging. Results: A total of 30 men (mean age, 42.3 +/- 10.0 years; bodymass index, 33.7 +/- 4.1 kg/m(2)) were included in this study. A moderate (8.0%) weight reduction occurred. Reversion of MetS was observed in 15 (50%) participants after the WRP. There was significant reduction in SAFA (68.3 +/- 20.2 vs. 51.5 +/- 18.6 cm(2); P < 0.001) and IAFA (96.3 +/- 15.6 vs. 86.0 +/- 16.5 cm(2); P < 0.001); the magnitude of reduction was greater for SAFA than for IAFA (-16.8 +/- 7.7 vs. -10.3 +/- 8.3 cm(2); P < 0.001). Multivariate logistic regression analysis showed a reduction in IAFA to be an independent factor to decrease the risk of persistent MetS after WRP by adjustment for age, baseline IAFA, and change in SAFA (odds ratio = 0.25, 95% confidence interval: 0.07-0.95, P = 0.041). Reduction in SAFA was not significantly associated with the reversion of MetS (P = 0.411). Conclusion: Reduction in IAFA via a 12-week WRP may help reverse MetS in men with obesity and MetS.
    URI: http://dx.doi.org/10.2147/DMSO.S228954
    https://www.webofscience.com/wos/woscc/full-record/WOS:000511389000001
    https://ir.csmu.edu.tw:8080/handle/310902500/24774
    關聯: DIABETES METABOLIC SYNDROME AND OBESITY-TARGETS AND THERAPY ,2020 ,v13 ,p1-8
    显示于类别:[中山醫學大學研究成果] 期刊論文

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