中山醫學大學機構典藏 CSMUIR:Item 310902500/24705
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    题名: Human papillomavirus infection associated with increased risk of new-onset psoriasis: a nationwide population-based cohort study
    作者: Chen, ML;Kao, WM;Huang, JY;Hung, YM;Wei, JCC
    关键词: Papillomavirus infection;psoriasis;cohort study
    日期: 2020
    上传时间: 2022-08-09T08:06:41Z (UTC)
    出版者: OXFORD UNIV PRESS
    ISSN: 0300-5771
    摘要: Background: This study investigated whether patients with a history of human papillomavirus (HPV) infection are at increased risk of developing psoriasis. Methods: We enrolled 66 274 patients with HPV infection between 1997 and 2013 from the Taiwan National Health Insurance Research Database, and compared them with control individuals who had never been diagnosed with HPV infection (at a 1:4 ratio matched by age, sex and index year) in relation to the risk of developing psoriasis. Cox proportional hazards models were used to estimate hazard ratios (HRs) and 95% confidence intervals (CIs), with the control group as reference. Results: The adjusted hazard ratio (aHR) was 1.177 (95% CI, 1.010-1.373) after adjusting for demographic characteristics, comorbidities, dermatology-related outpatient visits and medications. The HPV group had an increased risk of psoriasis compared with the control group in all of the different age groups. The P-value for interaction between age and exposure of HPV is 0.009 in our sub-group analysis. Conclusions: A higher risk of psoriasis was found after HPV infection, and age acted as an effect modifier between the HPV infection and risk of psoriasis.
    URI: http://dx.doi.org/10.1093/ije/dyaa027
    https://www.webofscience.com/wos/woscc/full-record/WOS:000593364900014
    https://ir.csmu.edu.tw:8080/handle/310902500/24705
    關聯: INTERNATIONAL JOURNAL OF EPIDEMIOLOGY ,2020 ,v49 ,issue 3 ,p786-797
    显示于类别:[中山醫學大學研究成果] 期刊論文

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