Long-term outcomes of trans-oral robotic surgery-assisted total laryngectomy for recurrent laryngeal cancers

doi:10.1093/jjco/hyaa034

中山醫學大學機構典藏 CSMUIR > 中山醫學大學研究成果 > 期刊論文 > Item 310902500/24697

Please use this identifier to cite or link to this item: https://ir.csmu.edu.tw:8080/ir/handle/310902500/24697

Title:	Long-term outcomes of trans-oral robotic surgery-assisted total laryngectomy for recurrent laryngeal cancers
Authors:	Wang, CC;Lin, WJ;De Virgilio, A;Liu, SA;Chen, SH;Liao, JS
Keywords:	laryngeal cancer;robotic surgery;swallowing;total laryngectomy;trans-oral
Date:	2020
Issue Date:	2022-08-09T08:06:33Z (UTC)
Publisher:	OXFORD UNIV PRESS
ISSN:	0368-2811
Abstract:	Objective: For recurrent laryngeal cancers, trans-oral robotic surgery has been used to perform total laryngectomy, but limited cases had been reported without long-term outcome follow-up. This study aims at presenting the largest longitudinal retrospective cohort in a single tertiary referral medical center. Methods: From November 2013 to August 2017, seven patients with recurrent laryngeal cancers without evidence of neck metastasis were selected to receive trans-oral robotic surgery-assisted TL without neck dissection. The para-operative details including the surgical success rates, surgical methods, resection extent, drainage tube placement, pharyngeal wound closure, console surgical time, pathologic findings and long-term complications were reviewed and described. The study end points include survival rates and preservation of swallowing function without tube feeding. Results: Trans-oral robotic surgery-assisted total laryngectomy was successfully performed on all seven patients with mean surgical console time of 111 +/- 66 min. Strap muscles and hyoid bone were resected like open surgery in six and five patients, respectively. For all the seven patients, there was no severe pharyngo-cutaneous fistula formation requiring repair in a second surgery, but tracheostoma stenosis was not uncommon (57%). Three patients received adjuvant chemotherapy/radiotherapy. After follow-up of 36.1 +/- 15.8 months, two patients had neck recurrence, and one patient died 19 months after surgery, but the other five patients were alive without disease recurrence. The overall survival rate was 85.7% (6/7), and all patients had good swallowing function without tube feeding. Conclusions: Trans-oral robotic surgery-assisted total laryngectomy is a feasible approach for selected patients with recurrent laryngeal cancers. The oncologic and functional outcomes were satisfactory. Further larger cohort study is worthwhile to further elucidate the value of trans-oral robotic surgery-assisted total laryngectomy.
URI:	http://dx.doi.org/10.1093/jjco/hyaa034 https://www.webofscience.com/wos/woscc/full-record/WOS:000544165300004 https://ir.csmu.edu.tw:8080/handle/310902500/24697
Relation:	JAPANESE JOURNAL OF CLINICAL ONCOLOGY ,2020 ,v50 ,issue 6 ,p653-660
Appears in Collections:	[中山醫學大學研究成果] 期刊論文

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