中山醫學大學機構典藏 CSMUIR:Item 310902500/24632
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    題名: Efficacy and safety of single-session radiofrequency ablation for benign thyroid nodules of different sizes: a retrospective study
    作者: Lin, WC;Kan, NN;Chen, HL;Luo, SD;Tung, YC;Chen, WC;Chou, CK;Chi, SY;Chen, MH;Su, YY;Cheng, KL;Baek, JH
    關鍵詞: Radiofrequency ablation;thyroid nodules;nodule volume;complication;nodular echogenicity
    日期: 2020
    上傳時間: 2022-08-09T08:05:30Z (UTC)
    出版者: TAYLOR & FRANCIS LTD
    ISSN: 0265-6736
    摘要: Purpose To compare the effectiveness of radiofrequency ablation (RFA) for benign thyroid nodules (BTNs) among groups presenting with different nodule volumes. Materials and methods This retrospective study evaluated 186 patients with BTNs who underwent ultrasound guided RFA treatment. The BTNs were categorized into small (<= 10 ml); medium (10-30 ml); and large (>30 ml) according to the initial volume of BTNs before ablation. The RFA procedures were performed using the moving shot technique. The volume reduction ratio (VRR) of each nodule, cosmetic score, symptomatic score, and complications were analyzed at 1, 3, and 6 months after RFA treatment and the three groups compared. Results At 1-month follow-up, the large nodules group showed significantly greater VRR compared to the other two groups (small, 31.88% +/- 37.91; medium, 38.9% +/- 19.18; large, 48.7% +/- 20.43,p = .03). At 6-month follow-up, there was no significant difference of VRR among the three groups (small, 74.6% +/- 20.92; medium, 68.1% +/- 17.07; large, 75.0% +/- 11.88). The most common presented complication was temporary vocal palsy (6 patients; small,n = 1; medium,n = 1; large,n = 3). Additionally, one skin burn, one hematoma, and one nodular rupture of BTNs occurred after the procedures. The complication rate of the large nodules group was highest among the three groups and showed a considerable difference (8 patients; small,n = 1, 2.1%; medium,n = 2, 4.5%; large,n = 5, 11.4%,p = .061). Conclusions RFA was confirmed as effective in patients with large thyroid nodule (>30ml), with therapeutic efficacy similar to patients with smaller thyroid nodules.
    URI: http://dx.doi.org/10.1080/02656736.2020.1782485
    https://www.webofscience.com/wos/woscc/full-record/WOS:000572272000001
    https://ir.csmu.edu.tw:8080/handle/310902500/24632
    關聯: INTERNATIONAL JOURNAL OF HYPERTHERMIA ,2020 ,v37 ,issue 1 ,p1082-1089
    顯示於類別:[中山醫學大學研究成果] 期刊論文

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