Efficacy and safety of single-session radiofrequency ablation for benign thyroid nodules of different sizes: a retrospective study

doi:10.1080/02656736.2020.1782485

中山醫學大學機構典藏 CSMUIR > 中山醫學大學研究成果 > 期刊論文 > Item 310902500/24632

Please use this identifier to cite or link to this item: https://ir.csmu.edu.tw:8080/ir/handle/310902500/24632

Title:	Efficacy and safety of single-session radiofrequency ablation for benign thyroid nodules of different sizes: a retrospective study
Authors:	Lin, WC;Kan, NN;Chen, HL;Luo, SD;Tung, YC;Chen, WC;Chou, CK;Chi, SY;Chen, MH;Su, YY;Cheng, KL;Baek, JH
Keywords:	Radiofrequency ablation;thyroid nodules;nodule volume;complication;nodular echogenicity
Date:	2020
Issue Date:	2022-08-09T08:05:30Z (UTC)
Publisher:	TAYLOR & FRANCIS LTD
ISSN:	0265-6736
Abstract:	Purpose To compare the effectiveness of radiofrequency ablation (RFA) for benign thyroid nodules (BTNs) among groups presenting with different nodule volumes. Materials and methods This retrospective study evaluated 186 patients with BTNs who underwent ultrasound guided RFA treatment. The BTNs were categorized into small (<= 10 ml); medium (10-30 ml); and large (>30 ml) according to the initial volume of BTNs before ablation. The RFA procedures were performed using the moving shot technique. The volume reduction ratio (VRR) of each nodule, cosmetic score, symptomatic score, and complications were analyzed at 1, 3, and 6 months after RFA treatment and the three groups compared. Results At 1-month follow-up, the large nodules group showed significantly greater VRR compared to the other two groups (small, 31.88% +/- 37.91; medium, 38.9% +/- 19.18; large, 48.7% +/- 20.43,p = .03). At 6-month follow-up, there was no significant difference of VRR among the three groups (small, 74.6% +/- 20.92; medium, 68.1% +/- 17.07; large, 75.0% +/- 11.88). The most common presented complication was temporary vocal palsy (6 patients; small,n = 1; medium,n = 1; large,n = 3). Additionally, one skin burn, one hematoma, and one nodular rupture of BTNs occurred after the procedures. The complication rate of the large nodules group was highest among the three groups and showed a considerable difference (8 patients; small,n = 1, 2.1%; medium,n = 2, 4.5%; large,n = 5, 11.4%,p = .061). Conclusions RFA was confirmed as effective in patients with large thyroid nodule (>30ml), with therapeutic efficacy similar to patients with smaller thyroid nodules.
URI:	http://dx.doi.org/10.1080/02656736.2020.1782485 https://www.webofscience.com/wos/woscc/full-record/WOS:000572272000001 https://ir.csmu.edu.tw:8080/handle/310902500/24632
Relation:	INTERNATIONAL JOURNAL OF HYPERTHERMIA ,2020 ,v37 ,issue 1 ,p1082-1089
Appears in Collections:	[中山醫學大學研究成果] 期刊論文

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