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    Please use this identifier to cite or link to this item: https://ir.csmu.edu.tw:8080/ir/handle/310902500/24606


    Title: Correction of Myopic Astigmatism with Topography-Guided Laser In Situ Keratomileusis (TOPOLINK)
    Authors: Wu, PL;Lee, CY;Cheng, HC;Lin, HY;Lai, LJ;Wu, WC;Chen, HC
    Keywords: refractive error;astigmatism;topography;laser in situ keratomileusis
    Date: 2020
    Issue Date: 2022-08-09T08:05:05Z (UTC)
    Publisher: MDPI
    Abstract: We aim to assess the feasibility of topography-guided laser in situ keratomileusis (TOPOLINK) for correcting pre-existing and surgical-induced astigmatism. A retrospective, single center cohort study was conducted. Patients with pre-existing irregular myopic astigmatism were recruited into the primary group and those with irregular myopic astigmatism following laser in situ keratomileusis (LASIK) were recruited into the enhancement group. The changes in uncorrected visual acuity (UCVA), best-corrected visual acuity (BCVA), maximum astigmatism, spherical equivalent (SE) and patient satisfaction were recorded. The Chi-square test, Mann-Whitney U test and Generalized Linear Mixed Model were utilized for the analysis in the current study. A total of 18 eyes were studied in the primary group and 14 eyes were examined in the enhancement group. One year postoperatively, the UCVA, BCVA, maximum astigmatism and SE improved significantly in both the primary and the enhancement groups (all p < 0.05). The UCVA (p = 0.046) and SE (p = 0.003) were worse in the primary group preoperatively but became similar in both groups postoperatively, while the BCVA and maximum astigmatism remained identical between groups throughout the study period (all p < 0.05). In addition, the rate of high and moderate satisfaction reached 90.0% in the primary and the enhancement groups, without significant differences (p = 0.871). In conclusion, the TOPOLINK showed high predictability and will contribute to similar outcomes between primary and postoperative irregular myopic astigmatism concerning visual acuity, refractive status and subject satisfaction.
    URI: http://dx.doi.org/10.3390/healthcare8040477
    https://www.webofscience.com/wos/woscc/full-record/WOS:000601431500001
    https://ir.csmu.edu.tw:8080/handle/310902500/24606
    Relation: HEALTHCARE ,2020 ,v8 ,issue 4
    Appears in Collections:[中山醫學大學研究成果] 期刊論文

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