中山醫學大學機構典藏 CSMUIR:Item 310902500/24536
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    题名: Risk Prediction for Early Chronic Kidney Disease: Results from an Adult Health Examination Program of 19,270 Individuals
    作者: Shih, CC;Lu, CJ;Chen, GD;Chang, CC
    关键词: early chronic kidney disease;machine learning;risk prediction
    日期: 2020
    上传时间: 2022-08-09T08:03:58Z (UTC)
    出版者: MDPI
    摘要: Developing effective risk prediction models is a cost-effective approach to predicting complications of chronic kidney disease (CKD) and mortality rates; however, there is inadequate evidence to support screening for CKD. In this study, four data mining algorithms, including a classification and regression tree, a C4.5 decision tree, a linear discriminant analysis, and an extreme learning machine, are used to predict early CKD. The study includes datasets from 19,270 patients, provided by an adult health examination program from 32 chain clinics and three special physical examination centers, between 2015 and 2019. There were 11 independent variables, and the glomerular filtration rate (GFR) was used as the predictive variable. The C4.5 decision tree algorithm outperformed the three comparison models for predicting early CKD based on accuracy, sensitivity, specificity, and area under the curve metrics. It is, therefore, a promising method for early CKD prediction. The experimental results showed that Urine protein and creatinine ratio (UPCR), Proteinuria (PRO), Red blood cells (RBC), Glucose Fasting (GLU), Triglycerides (TG), Total Cholesterol (T-CHO), age, and gender are important risk factors. CKD care is closely related to primary care level and is recognized as a healthcare priority in national strategy. The proposed risk prediction models can support the important influence of personality and health examination representations in predicting early CKD.
    URI: http://dx.doi.org/10.3390/ijerph17144973
    https://www.webofscience.com/wos/woscc/full-record/WOS:000557626300001
    https://ir.csmu.edu.tw:8080/handle/310902500/24536
    關聯: INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH ,2020 ,v17 ,issue 14
    显示于类别:[中山醫學大學研究成果] 期刊論文

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