中山醫學大學機構典藏 CSMUIR:Item 310902500/24504
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    题名: Graves' disease could increase polycystic ovary syndrome and comorbidities in Taiwan
    作者: Chen, HH;Chen, CC;Hsieh, MC;Ho, CW;Hsu, SP;Yip, HT;Kao, CH
    关键词: Graves' disease (GD);polycystic ovary syndrome (PCOS);hyperlipidemia
    日期: 2020
    上传时间: 2022-08-09T08:03:25Z (UTC)
    出版者: TAYLOR & FRANCIS LTD
    ISSN: 0300-7995
    摘要: Background: To investigate the association between Graves' disease (GD) and polycystic ovary syndrome (PCOS) and its comorbidities. Methods: Logistic regression was performed to determine the association between the two conditions. Cumulative incidence curves were obtained using the Kaplan-Meier method and log-rank test. Hazard ratios were determined using the Cox proportional hazards regression model. Results: We included 5399 patients with GD as the study group and 10,798 patients without GD as the control group. The cumulative incidence curve of PCOS in patients with GD was significantly higher than that in patients without GD (p = .02). The adjusted hazard ratio for PCOS in patients with GD compared with patients without GD was 1.47 (95%CI = 1.09-1.98). The adjusted odds ratio of hyperlipidemia in patients with GD and PCOS was 2.18 (95%CI = 1.14-4.17) higher than that in patients with GD only. Conclusion: Our study demonstrated that women with GD could be at risk of developing PCOS; additionally, a higher incidence of comorbidities, including hyperlipidemia, was noted in women with GD and PCOS.
    URI: http://dx.doi.org/10.1080/03007995.2020.1756235
    https://www.webofscience.com/wos/woscc/full-record/WOS:000532026700001
    https://ir.csmu.edu.tw:8080/handle/310902500/24504
    關聯: CURRENT MEDICAL RESEARCH AND OPINION ,2020 ,v36 ,issue 6 ,p1063-1067
    显示于类别:[中山醫學大學研究成果] 期刊論文

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