|
English
|
正體中文
|
简体中文
|
Items with full text/Total items : 17939/22958 (78%)
Visitors : 7367918
Online Users : 206
|
|
|
Loading...
|
Please use this identifier to cite or link to this item:
https://ir.csmu.edu.tw:8080/ir/handle/310902500/24503
|
Title: | Hashimoto's thyroiditis might increase polycystic ovary syndrome and associated comorbidities risks in Asia |
Authors: | Ho, CW;Chen, HH;Hsieh, MC;Chen, CC;Hsu, SP;Yip, HT;Kao, CH |
Keywords: | Hashimoto's thyroiditis (HT);polycystic ovary syndrome (PCOS);coronary artery disease (CAD) |
Date: | 2020 |
Issue Date: | 2022-08-09T08:03:24Z (UTC)
|
Publisher: | AME PUBL CO |
ISSN: | 2305-5839 |
Abstract: | Background: To investigate whether increased the comorbidities such as coronary artery disease (CAD) and risks between Hashimoto's thyroiditis (HT) and polycystic ovary syndrome ( PCOS) in Taiwanese women. Methods: Patients newly diagnosed as having HT during 2000-2012 were assigned to the case group. Cases and controls were matched for age and comorbidities at a 1:2 ratio using propensity score matching. Incidence was calculated in the unit of 1000 person-year. Univariate and multivariate Cox proportional hazard regression, multivariate Cox, logistic regression, and Kaplan-Meier analyses were performed. Results: Among 3,996 participants, 2,664 constituted the control group and 1,332 constituted the case group. The PCOS risk in patients with HT increased by 2.37 times [95% confidence interval (CI): 1.22-4.62] compared with the controls. Hypertension (HTN) [adjusted odds ratio (OR): 1.31, 95% CI: 1.03-1.66] and hyperlipidemia (adjusted OR: 1.55, 95% CI: 1.2-1.9) were more common in HT patients without PCOS than in other patients. The adjusted OR for CAD in patients with HT was 1.51 (95% CI: 1.11-2.06), whereas that in patients with HT and PCOS was 5.92 (95% CI: 1.32-26.53). Conclusions: In our study, the PCOS risk in patients with HT increased by 2.37 times, which is lower than the increase in HT risk in Asian patients with PCOS (4.56 times). The proportion of CAD increased significantly by 5.92 times in patients with HT and PCOS compared with patients with HT only. |
URI: | http://dx.doi.org/10.21037/atm-19-4763 https://www.webofscience.com/wos/woscc/full-record/WOS:000541834200024 https://ir.csmu.edu.tw:8080/handle/310902500/24503 |
Relation: | ANNALS OF TRANSLATIONAL MEDICINE ,2020 ,v8 ,issue 11 |
Appears in Collections: | [中山醫學大學研究成果] 期刊論文
|
Files in This Item:
File |
Description |
Size | Format | |
index.html | | 0Kb | HTML | 284 | View/Open |
|
All items in CSMUIR are protected by copyright, with all rights reserved.
|