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    Please use this identifier to cite or link to this item: https://ir.csmu.edu.tw:8080/ir/handle/310902500/24440


    Title: Study protocol to investigate the correlation between Tourette syndrome and allergy in children and adolescents
    Authors: Tsai, LH;Lin, JW;Lue, KH
    Keywords: Allergen;allergic disease;neuropsychiatric disorders;Tourette syndrome;children and adolescents;survey
    Date: 2020
    Issue Date: 2022-08-09T08:02:20Z (UTC)
    Publisher: SAGE PUBLICATIONS LTD
    ISSN: 0300-0605
    Abstract: Objective Noting that the usefulness of cases diagnosed in administrative registers is dependent on diagnostic validity, in this study, we aim to elucidate the correlation between Tourette syndrome and allergy in children and adolescents, specifically with regard to incidence of asthma, allergic rhinitis, allergic conjunctivitis, and atopic dermatitis. Methods Based on a set of inclusion and exclusion criteria, we intend to enroll 200 children and adolescents aged 18 years and younger, accompanied by their parents, for a duration of 2 years. We will administer an anonymous questionnaire in a case-control study. We will use the chi-squared test to evaluate differences between cases and controls. Results According to the European Review for Medical and Pharmacological Sciences, the proportion of allergic diseases expected in patients with Tourette syndrome is 53.1% (17/32) and 22.9% (8/35) in the controls. Setting the type 1 error to 0.05 and the power to 0.8, we will ensure a 1:2 case-to-control ratio. Conclusions This study protocol describes our analysis of anonymous questionnaire responses. Comorbidity rates, environmental factors, and genetic factors for various allergens, allergies, and other neuropsychiatric disorders will be studied.
    URI: http://dx.doi.org/10.1177/0300060520973921
    https://www.webofscience.com/wos/woscc/full-record/WOS:000596408500001
    https://ir.csmu.edu.tw:8080/handle/310902500/24440
    Relation: JOURNAL OF INTERNATIONAL MEDICAL RESEARCH ,2020 ,v48 ,issue 12
    Appears in Collections:[中山醫學大學研究成果] 期刊論文

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