Correlations between severity of anterior vaginal wall prolapse and parameters of urethral pressure profile

doi:10.1111/luts.12357

中山醫學大學機構典藏 CSMUIR > 中山醫學大學研究成果 > 期刊論文 > Item 310902500/24306

Please use this identifier to cite or link to this item: https://ir.csmu.edu.tw:8080/ir/handle/310902500/24306

Title:	Correlations between severity of anterior vaginal wall prolapse and parameters of urethral pressure profile
Authors:	Chang, HW;Ng, SC;Chen, GD
Keywords:	anterior vaginal wall prolapse;cystocele;maximal urethral pressure;urethral pressure;urethral pressure profile
Date:	2021
Issue Date:	2022-08-09T08:00:09Z (UTC)
Publisher:	WILEY
ISSN:	1757-5664
Abstract:	Objective Previous studies have shown that anterior vaginal wall prolapse (AVWP) results in reduction of pressure in the proximal urethra. However, the effect of severity of AVWP on urethral pressure is controversial. This study aimed to evaluate parameters of the urethral pressure profile in different stages of AVWP. Materials and methods From 2016 to 2017, 286 consecutive patients with urogynecologic complaints who were referred to our urodynamic unit were enrolled in this study to analyze their urethral pressure profiles. Stages of AVWP were regrouped into three groups ranging from mild to severe stages (groups 1-3). Maximal urethral pressure, urethral closure pressure, functional urethral length, length of continence zone, as well as area of continence zone were compared among these three groups. Results Distribution of age, parity, and menopausal women were significantly different among these three groups. Maximal urethral pressure (pressures for groups 1, 2, and 3 were 74.6 similar to 75.9cmH2O, 69.7 similar to 73.4cmH2O, and 58.3 similar to 60.5cmH2O, respectively; all P<.05) and stress urethral closure pressure (pressures for groups 1, 2, and 3 were 69.3cmH2O, 62.3cmH2O, and 52.2cmH2O, respectively; all P<.05) gradually and significantly decreased, consistent with the severity of AVWP. However, the attenuated maximal urethral pressure and stress urethral closure pressure in accordance with severity did not show any significant difference after controlling for age, body mass index, parity, menopause, and stress urinary incontinence symptoms. Conclusion Our results showed that AVWP significantly attenuated urethral pressure. However, patient age, menopausal status, and number of parities seem to be more influential in compromising urethral function than just AVWP alone.
URI:	http://dx.doi.org/10.1111/luts.12357 https://www.webofscience.com/wos/woscc/full-record/WOS:000591288300001 https://ir.csmu.edu.tw:8080/handle/310902500/24306
Relation:	LUTS-LOWER URINARY TRACT SYMPTOMS ,2021 ,v13 ,issue 2 ,p238-243
Appears in Collections:	[中山醫學大學研究成果] 期刊論文

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