Epidemiology and factors associated with mortality of thyroid storm in Taiwan: a nationwide population-based study

doi:10.1007/s11739-020-02445-6

中山醫學大學機構典藏 CSMUIR > 中山醫學大學研究成果 > 期刊論文 > Item 310902500/24302

Please use this identifier to cite or link to this item: https://ir.csmu.edu.tw:8080/ir/handle/310902500/24302

Title:	Epidemiology and factors associated with mortality of thyroid storm in Taiwan: a nationwide population-based study
Authors:	Kornelius, E;Chang, KL;Yang, YS;Huang, JY;Ku, MS;Lee, KY;Ho, SW
Keywords:	Epidemiology;Mortality;Population-based study;Thyroid storm
Date:	2021
Issue Date:	2022-08-09T08:00:05Z (UTC)
Publisher:	SPRINGER-VERLAG ITALIA SRL
ISSN:	1828-0447
Abstract:	Thyroid storm is a rare and life-threatening disease. However, its prevalence, incidence, and mortality rate in Chinese population are unknown. We performed a retrospective study using the Taiwan Health and Welfare Data. Patients admitted owing to thyrotoxicosis were divided into thyroid storm group and non-thyroid storm group. We assessed thyroid storm prevalence, incidence, complications, and mortality rate. Multiple Cox regression was performed to estimate the hazard ratio for the mortality risk. Overall, 1244 thyroid storm patients and 83,874 thyrotoxicosis patients without thyroid storm were included. Most thyroid storm patients were female (67.9%) with ages ranging from 30 to 44 years (33.4%), and most thyroid storm cases occurred during the summer season. The prevalence of thyroid storm was 1.48% (1244/83,874). The incidence rate of thyroid storm was 0.55 per 100,000 persons per year and 6.28 per 100,000 hospitalized patients per year. The overall 14-, 28-, and 90-day mortality rates of thyroid storm patients were 5.23%, 6.59%, and 8.12%, respectively. Thyroid storm, older age, male, and underlying ischemic stroke, myocardial infarction, heart failure, kidney disease, atrial fibrillation, depression, chronic obstructive pulmonary disease, diabetes mellitus, cancer, end stage renal diseases were associated with a significantly higher risk of mortality. In conclusion, the 90-day mortality rate of thyroid storm was high and was commonly associated with multiorgan failure and shock. Therefore, clinical physicians should identify thyroid storm and treat it accordingly.
URI:	http://dx.doi.org/10.1007/s11739-020-02445-6 https://www.webofscience.com/wos/woscc/full-record/WOS:000549237800002 https://ir.csmu.edu.tw:8080/handle/310902500/24302
Relation:	INTERNAL AND EMERGENCY MEDICINE ,2021 ,v16 ,issue 3 ,p601-607
Appears in Collections:	[中山醫學大學研究成果] 期刊論文

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