The effect of sumac (Rhus coriaria L.) supplementation on glycemic indices: A systematic review and meta-analysis of controlled clinical trials

doi:10.1016/j.ctim.2021.102766

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Please use this identifier to cite or link to this item: https://ir.csmu.edu.tw:8080/ir/handle/310902500/24192

Title:	The effect of sumac (Rhus coriaria L.) supplementation on glycemic indices: A systematic review and meta-analysis of controlled clinical trials
Authors:	Mohit, M;Nouri, M;Samadi, M;Nouri, Y;Heidarzadeh-Esfahani, N;Venkatakrishnan, K;Jalili, C
Keywords:	Sumac;Rhus coriaria;Glycemic indices;Systematic review;Meta-analysis
Date:	2021
Issue Date:	2022-08-05T10:44:35Z (UTC)
Publisher:	CHURCHILL LIVINGSTONE
ISSN:	0965-2299
Abstract:	Background & aims: Rhus coriaria L. (Sumac) is a popular spice/herb with several biological functions owing to its antioxidant and insulin-like activities. Many clinical trials have indicated the potent anti-diabetic property of sumac but the results on few glycemic indices were inconclusive. Hence, this systematic review and metaanalysis were aimed to investigate sumac supplementation effect on glycemic indices. Methods: Systematically searched was performed by two independent reviewers using online databases including: PubMed, Scopus, web of science, EMBASE from inception until November 2020. Data were pooled using a random-effects model and weighted mean difference (WMD) with 95 % confidence intervals (CI). Results: A total of 6 potentially relevant clinical trials met the inclusion criteria with total of 278 participants. Random-effects meta-analysis suggested no significant effects on the levels of fasting blood glucose [-7.08 mg/dl, 95 % CI: -14.85 to 0.70,P = 0.07, I2 = 59.8 %], glycosylated hemoglobin (HbA1c) [-0.48 %, 95 % CI: -1.01 to -0.04, P = 0.07, I2 = 0.0 %], homeostatic model assessment for insulin resistance (HOMA-IR) [-0.97, 95 % CI: -1.96 to 0.02, P = 0.05, I2 = 83.8 %], and insulin [-2.94 Hedges' g, 95 % CI: -6.67 to 0.80, P = 0.12, I2 = 83.1 %] following supplementation with sumac powder. Conclusion: This meta-analysis showed no significant effects on any glycemic indices following supplementation with sumac powder.
URI:	http://dx.doi.org/10.1016/j.ctim.2021.102766 https://www.webofscience.com/wos/woscc/full-record/WOS:000700589400003 https://ir.csmu.edu.tw:8080/handle/310902500/24192
Relation:	COMPLEMENTARY THERAPIES IN MEDICINE ,2021 ,v61
Appears in Collections:	[中山醫學大學研究成果] 其他文獻

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