中山醫學大學機構典藏 CSMUIR:Item 310902500/24053
English  |  正體中文  |  简体中文  |  全文笔数/总笔数 : 17918/22933 (78%)
造访人次 : 7419996      在线人数 : 271
RC Version 7.0 © Powered By DSPACE, MIT. Enhanced by NTU Library IR team.
搜寻范围 查询小技巧：
  • 您可在西文检索词汇前后加上"双引号"，以获取较精准的检索结果
  • 若欲以作者姓名搜寻，建议至进阶搜寻限定作者字段，可获得较完整数据
    •  进阶搜寻


    jsp.display-item.identifier=請使用永久網址來引用或連結此文件: https://ir.csmu.edu.tw:8080/ir/handle/310902500/24053


    题名: Features of indeterminate results of QuantiFERON-TB Gold In-Tube test in patients with haematological malignancies
    作者: Huang, CC;Teng, CLJ;Wu, MF;Lee, CH;Chen, HC;Huang, WC
    关键词: haematological malignancy;indeterminate;QuantiFERON-TB Gold in-Tube
    日期: 2021
    上传时间: 2022-08-05T09:47:04Z (UTC)
    出版者: SAGE PUBLICATIONS LTD
    ISSN: 2040-6207
    摘要: Background and aims: The application of QuantiFERON-TB Gold in-Tube (QFT-GIT) in patients with haematological malignancies (HMs) has not been well studied. Therefore, we aimed to investigate the features of patients with HMs whose QFT-GIT results were indeterminate. Methods: This study enrolled patients with HMs for the analysis of QFT-GIT tests and additional 2-year follow-up. The characteristics and predictors of QFT-GIT indeterminate results were identified. Mycobacterium tuberculosis (TB) incidence rate (IR) and incidence rate ratio (IRR) were also investigated. Results: Of 89 participants, 27 (30.3%) had QFT-GIT indeterminate results. The QFT-GIT indeterminate patients were characterized with the diagnosis of leukaemia (63.0% versus 32.3%, p=0.044), abnormal white blood count (WBC) (88.9% versus 14.5%, p=0.001), abnormal lymphocyte percentage (81.5% versus 14.5%, p=0.001) and lower lymphocyte count (x10(9)/l) (0.5 versus 2.2, p=0.000) when compared with those with determinate results. Meanwhile, abnormal WBC [odds ratios (OR): 15.18, p=0.003] and lymphocyte percentage (OR: 6.90, p=0.033) were predictors of indeterminate results. One patient with the QFT-GIT indeterminate status and high interferon-gamma level of negative control result developed active TB with a TB IR of 18.5 per 1000 person-years and an IRR of 0.1 (95% confidence interval, 0.01-0.71) when compared with positive QFT-GIT patients without prophylaxis treatment. Conclusion: Abnormal ranges of WBC and lymphocyte differential count percentage were independent predictors useful to determine the optimal timing of implementing QFT-GIT test in patients with HMs.
    URI: http://dx.doi.org/10.1177/20406207211028437
    https://www.webofscience.com/wos/woscc/full-record/WOS:000688008600001
    https://ir.csmu.edu.tw:8080/handle/310902500/24053
    關聯: THERAPEUTIC ADVANCES IN HEMATOLOGY ,2021,v12
    显示于类别:[中山醫學大學研究成果] 期刊論文

    文件中的档案:

    档案 描述 大小格式浏览次数
    index.html0KbHTML210检视/开启


    SFX Query

    在CSMUIR中所有的数据项都受到原著作权保护.

    TAIR相关文章

    DSpace Software Copyright © 2002-2004  MIT &  Hewlett-Packard  /   Enhanced by   NTU Library IR team Copyright ©   - 回馈