中山醫學大學機構典藏 CSMUIR:Item 310902500/24000
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    题名: Association Between Aspirin Use and Decreased Risk of Pneumonia in Patients With Cardio-Cerebra-Vascular Ischemic Disease: A Population-Based Cohort Study
    作者: Chen, YC;Chen, YY;Yeh, HW;Yeh, TY;Huang, JY;Liao, PL;Yeh, LT;Yang, SF;Chou, MC;Yeh, CB
    关键词: aspirin;pneumonia;risk;database;cardio-cerebra-vascular ischemic diseases
    日期: 2021
    上传时间: 2022-08-05T09:46:14Z (UTC)
    出版者: FRONTIERS MEDIA SA
    摘要: This study evaluated the association between long-term low-dose aspirin use and decreased risk of pneumonia in patients with cardio-cerebra-vascular ischemic diseases (CCVDs). This retrospective cohort study used records from Taiwan's National Health Insurance Research Database of claims made between 1997 and 2013. After propensity score matching (PSM), patients who took a low dose of aspirin for more than 90 days within 1 year of diagnosis with CCVDs were identified as the exposure group (n = 15,784). A matched total of 15,784 individuals without aspirin use were selected for the non-aspirin group. The main outcome was the development of pneumonia after the index date. Multivariable Cox regression analysis and Kaplan-Meier survival analysis were performed to estimate the adjusted hazard ratio (aHR) and cumulative probability of pneumonia. The result after PSM indicated a lower hazard ratio for pneumonia in aspirin users (aHR = 0.890, 95% confidence interval = 0.837-0.945). Therefore, patients with CCVDs who took aspirin had a lower risk of developing pneumonia than those who did not. In conclusion, this population-based cohort study demonstrated that long-term low-dose aspirin use is associated with a slightly decreased risk of pneumonia in patients with CCVDs.
    URI: http://dx.doi.org/10.3389/fpubh.2021.625834
    https://www.webofscience.com/wos/woscc/full-record/WOS:000635558100001
    https://ir.csmu.edu.tw:8080/handle/310902500/24000
    關聯: FRONTIERS IN PUBLIC HEALTH ,2021,v9
    显示于类别:[中山醫學大學研究成果] 期刊論文

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