Effects of electrode plate annealing treatment and the addition of hydrogen peroxide on improving the degradation of cobalt hydroxyapatite for bone repair

doi:10.1016/j.matchemphys.2020.123962

中山醫學大學機構典藏 CSMUIR > 中山醫學大學研究成果 > 期刊論文 > Item 310902500/23964

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题名:	Effects of electrode plate annealing treatment and the addition of hydrogen peroxide on improving the degradation of cobalt hydroxyapatite for bone repair
作者:	Tang, CM;Fan, FY;Ke, YC;Lin, WC
关键词:	Cobalt-hydroxyapatite;Titanium dioxide nanotubes;Hydrogen peroxide;Magnetic property;Biodegradability;Non-crystalline solids
日期:	2021
上传时间:	2022-08-05T09:45:40Z (UTC)
出版者:	ELSEVIER SCIENCE SA
ISSN:	0254-0584
摘要:	Hydroxyapatite (HA) is not easily degraded in the body, and currently this is still a huge challenge. In this study, we investigated (1) crystal-phase transformation of an electrode plate and (2) the addition of hydrogen peroxide as methods to improve biodegradation for cobalt-HA (CoHA). Results show that the addition of a high concentration of hydrogen peroxide will significantly reduce the crystallinity and particle size of CoHA. In addition, the biodegradability of CoHA was evaluated by immersion in phosphate-buffered saline. The pH value of PBS increased with an increasing H2O2 concentration and release of cobalt ions. Moreover, the pH value and the release curve of cobalt ions showed that the addition of hydrogen peroxide achieved better biodegradation than did a change in the crystal phase of the electrode plate. We confirmed that the addition of hydrogen peroxide can effectively improve CoHA's degradation behavior in simulated body fluid.
URI:	http://dx.doi.org/10.1016/j.matchemphys.2020.123962 https://www.webofscience.com/wos/woscc/full-record/WOS:000615731600004 https://ir.csmu.edu.tw:8080/handle/310902500/23964
關聯:	MATERIALS CHEMISTRY AND PHYSICS ,2021,v259
显示于类别:	[中山醫學大學研究成果] 期刊論文

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