Bilateral Vertebral Artery Hypoplasia and Fetal-Type Variants of the Posterior Cerebral Artery in Acute Ischemic Stroke

doi:10.3389/fneur.2021.582149

中山醫學大學機構典藏 CSMUIR > 中山醫學大學研究成果 > 期刊論文 > Item 310902500/23954

Please use this identifier to cite or link to this item: https://ir.csmu.edu.tw:8080/ir/handle/310902500/23954

Title:	Bilateral Vertebral Artery Hypoplasia and Fetal-Type Variants of the Posterior Cerebral Artery in Acute Ischemic Stroke
Authors:	Hsu, CF;Chen, KW;Su, CH;Shen, CY;Chi, HY
Keywords:	posterior circulation infarction;vertebral artery hypoplasia;posterior cerebral artery;vertebrobasilar insufficiency;ultrasonagraphy
Date:	2021
Issue Date:	2022-08-05T09:45:31Z (UTC)
Publisher:	FRONTIERS MEDIA SA
ISSN:	1664-2295
Abstract:	Aim: Unilateral vertebral artery hypoplasia is considered a risk factor for posterior circulation infarction. Despite the increasing attention on unilateral vertebral artery hypoplasia, few studies have discussed bilateral vertebral artery hypoplasia, its influence on stroke, or its collateral supply from the circle of Willis. We aimed to identify its characteristics, stroke pattern, and unique ultrasonographic and brain imaging findings. Materials and Methods: Of the 1,301 consecutive in-patients diagnosed with acute ischemic stroke from January 2013 to December 2015, medical and laboratory data and stroke or transient ischemic attack history were recorded. We enrolled patients who underwent both brain magnetic resonance imaging and sonography examinations. Vertebral artery and posterior cerebral artery analyses were conducted in accordance with clinical criteria. Results: Adequate imaging data were available for 467 patients. Of these, eight patients met the criteria for bilateral vertebral artery hypoplasia. The mean age was 62.9 +/- 12.1 years. There were six male (75.0%) and two female patients (25.0%). A high prevalence of hypertension (7/8, 87.5%) was noted. Sonograms displayed a very low net flow volume in the vertebral arteries, with the average net flow volume being 28.9 +/- 9.7 mL/min. A high frequency (6/8; 75.0%) of the fetal variant posterior cerebral artery from the carotids was found. The infarction patterns in these patients were all bilateral, scattered, and in multiple vascular territories. Conclusion: Patients with bilateral vertebral hypoplasia displayed a unique collateral supply, special stroke pattern, and younger stroke onset. Early recognition and stroke prevention should be considered critical in clinical practice.
URI:	http://dx.doi.org/10.3389/fneur.2021.582149 https://www.webofscience.com/wos/woscc/full-record/WOS:000642090600001 https://ir.csmu.edu.tw:8080/handle/310902500/23954
Relation:	FRONTIERS IN NEUROLOGY ,2021,v12
Appears in Collections:	[中山醫學大學研究成果] 期刊論文

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