Quick screening of true tyrosinase inhibitors from natural products using tyrosinase-immobilized magnetic nanoparticles and a magnetic microplate: Part II melanogenesis bioactivity

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题名:	Quick screening of true tyrosinase inhibitors from natural products using tyrosinase-immobilized magnetic nanoparticles and a magnetic microplate: Part II melanogenesis bioactivity
作者:	Tsai, HY;Hsieh, CC;Chang, YC;Lin, YC;Chen, SF
关键词:	abscisic acid;melanogenesis;tyrosinase inhibitors
日期:	2021
上传时间:	2022-08-05T09:42:38Z (UTC)
出版者:	WILEY-V C H VERLAG GMBH
ISSN:	0009-4536
摘要:	We previously reported a rapid method for screening true tyrosinase inhibitors. Here, the identified active component from litchi flower extract was further confirmed using a tyrosinase inhibitory assay and inhibitory effects on melanogenesis of murine melanoma B16-F1 cell to prove its bioactivity. This is the first report regarding the inhibitory effect of abscisic acid on melanogenesis. The crude extraction of litchi flower showed some degree of cell toxicity. This report would also like to remind people who want to use crude extraction of herbs to carefully check their toxicological test reports.
URI:	http://dx.doi.org/10.1002/jccs.202100344 https://www.webofscience.com/wos/woscc/full-record/WOS:000698860200001 https://ir.csmu.edu.tw:8080/handle/310902500/23773
關聯:	JOURNAL OF THE CHINESE CHEMICAL SOCIETY ,2021,v68,issue 12, P2290-2293
显示于类别:	[中山醫學大學研究成果] 期刊論文

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