Non-Thermal Reactive N-2/He Plasma Exposure to Inhibit Epithelial Head and Neck Tumor Cells

中山醫學大學機構典藏 CSMUIR > 中山醫學大學研究成果 > 期刊論文 > Item 310902500/23736

Please use this identifier to cite or link to this item: https://ir.csmu.edu.tw:8080/ir/handle/310902500/23736

Title:	Non-Thermal Reactive N-2/He Plasma Exposure to Inhibit Epithelial Head and Neck Tumor Cells
Authors:	Wu, CY;Liao, JD;Chen, CH;Lee, H;Wang, SH;Liu, BH;Lee, CY;Shao, PL;Li, EY
Keywords:	non-thermal micro-plasma; reactive oxygen/nitrogen species ;cancer cell suppression
Date:	2021
Issue Date:	2022-08-05T09:42:02Z (UTC)
Publisher:	MDPI
Abstract:	The traditional therapy for head and neck cancer patients has several side effects. Hence, regular follow-up care is usually required. Recently, non-thermal micro-plasma was applied to inactivate cancer cells. Such a physical method provides localized energy and reactive oxygen/nitrogen species (ROS/RNS). In this study, the ability of non-oxygen N-2/He micro-plasma to inactivate four pharynx squamous carcinomatous cells, namely SAS, CAL 27, FaDu, and Detroit 562, under different exposure durations is evaluated. The four cell lines were affected with regard to proliferation, reduction, and apoptosis-related DNA damage, implying that the cell medium is critical in plasma-cell interaction. This is expected to be a promising method for head and neck cancer cell suppression through plasma-initiated ROS/RNS species under a suitable exposure time.
URI:	http://dx.doi.org/10.3390/coatings11111284 https://www.webofscience.com/wos/woscc/full-record/WOS:000724543800001 https://ir.csmu.edu.tw:8080/handle/310902500/23736
Relation:	COATINGS ,2021,v11,issue 11
Appears in Collections:	[中山醫學大學研究成果] 期刊論文

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