中山醫學大學機構典藏 CSMUIR:Item 310902500/23727
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    题名: The Impact of Clinical Atropine Use in Taiwanese Schoolchildren: Changes in Physiological Characteristics and Visual Functions
    作者: Kuo, HY;Ke, CH;Chen, ST;Sun, HY
    关键词: myopia control;atropine;the amplitude of accommodation;pupil size;intraocular pressure;visual complaint
    日期: 2021
    上传时间: 2022-08-05T09:41:54Z (UTC)
    出版者: MDPI
    摘要: Taiwan is commonly noted for its high prevalence of myopia, as well as a long history of more than 20 years of using atropine to control myopia. However, the clinical implications are rarely discussed. This is a cross-sectional study investigating the influence of topical atropine instillation on ocular physiology, visual function, and visual discomfort in children. Aged 7 to 12 years, 212 schoolchildren were recruited and divided into the atropine group and the non-atropine group. Physiological characteristics such as pupil size and intraocular pressure were measured, and a variety of visual functions was also evaluated. A questionnaire was used to investigate the side effects and visual complaints caused by atropine treatment. There was a significant difference in pupil size (OD: 5.40 +/- 0.90 vs. 6.60 +/- 1.01 mm; OS: 5.42 +/- 0.87 vs. 6.64 +/- 1.00 mm, p < 0.001) between the two groups. Reductions in near visual acuity, accommodation, convergence ability, and stereopsis were observed in the atropine group. The horizontal pupil diameter enlarged, and visual functions were greatly affected after administration of topical atropine. The changes in visual function during atropine therapy need to be carefully monitored by clinicians, while patient compliance is usually the key to success.
    URI: http://dx.doi.org/10.3390/children8111054
    https://www.webofscience.com/wos/woscc/full-record/WOS:000807136800001
    https://ir.csmu.edu.tw:8080/handle/310902500/23727
    關聯: CHILDREN-BASEL ,2021,v8,issue 11
    显示于类别:[中山醫學大學研究成果] 期刊論文

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