中山醫學大學機構典藏 CSMUIR:Item 310902500/23630
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    题名: The Correlations between Horizontal and Vertical Peripheral Refractions and Human Eye Shape Using Magnetic Resonance Imaging in Highly Myopic Eyes
    作者: Kuo, HY;Hsiao, JCJ;Chen, JJ;Lee, CH;Chuang, CC;Sun, HY
    关键词: high myopia;peripheral refraction;magnetic resonance imaging;ocular shape
    日期: 2021
    上传时间: 2022-08-05T09:40:22Z (UTC)
    出版者: MDPI
    摘要: The aim of this study was to determine the relationship between relative peripheral refraction and retinal shape by 2-D magnetic resonance imaging in high myopes. Thirty-five young adults aged 20 to 30 years participated in this study with 16 high myopes (spherical equivalent < -6.00 D) and 19 emmetropes (+0.50 to -0.50 D). An open field autorefractor was used to measure refractions from the center out to 60 degrees in the horizontal meridian and out to around 20 degrees in the vertical meridian, with a step of 3 degrees. Axial length was measured by using A-scan ultrasonography. In addition, images of axial, sagittal, and tangential sections were obtained using 2-D magnetic resonance imaging. The highly myopic group had a significantly relative peripheral hyperopic refraction and showed a prolate ocular shape compared to the emmetropic group. The highly myopic group had relative peripheral hyperopic refraction and showed a prolate ocular form. Significant differences in the ratios of height/axial (1.01 +/- 0.02 vs. 0.94 +/- 0.03) and width/axial (0.99 +/- 0.17 vs. 0.93 +/- 0.04) were found from the MRI images between the emmetropic and the highly myopic eyes (p < 0.001). There was a negative correlation between the retina's curvature and relative peripheral refraction for both temporal (Pearson r = -0.459; p < 0.01) and nasal (Pearson r = -0.277; p = 0.011) retina. For the highly myopic eyes, the amount of peripheral hyperopic defocus is correlated to its ocular shape deformation. This could be the first study investigating the relationship between peripheral refraction and ocular dimension in high myopes, and it is hoped to provide useful knowledge of how the development of myopia changes human eye shape.
    URI: http://dx.doi.org/10.3390/healthcare9080966
    https://www.webofscience.com/wos/woscc/full-record/WOS:000689307200001
    https://ir.csmu.edu.tw:8080/handle/310902500/23630
    關聯: HEALTHCARE ,2021,v9,issue 8
    显示于类别:[中山醫學大學研究成果] 期刊論文

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