Development of an Electrochemical Immunosensor for Detection of Cardiac Troponin I at the Point-of-Care

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题名:	Development of an Electrochemical Immunosensor for Detection of Cardiac Troponin I at the Point-of-Care
作者:	Lee, TH;Chen, LC;Wang, E;Wang, CC;Lin, YR;Chen, WL
关键词:	cardiac troponin I;immunosensor;point-of-care
日期:	2021
上传时间:	2022-08-05T09:40:04Z (UTC)
出版者:	MDPI
摘要:	Cardiac troponin I (cTnI) plays an important role in the assessment of various cardiac diseases. However, accurate detection of cTnI at the point-of-care (POC) remains unfeasible. In this study, we report the development of an electrochemical immunosensor designed for rapid and accurate cTnI detection in pre-hospital settings. Rapid cTnI analysis of whole blood samples was then performed. cTnI measurements were highly correlated with the results of the standard clinical laboratory method for cTnI detection. The results of this study suggest that the proposed POC immunosensor can deliver fast and accurate cTnI analysis in pre-hospital settings to achieve rapid diagnosis and guide patient management.
URI:	http://dx.doi.org/10.3390/bios11070210 https://www.webofscience.com/wos/woscc/full-record/WOS:000676139800001 https://ir.csmu.edu.tw:8080/handle/310902500/23610
關聯:	BIOSENSORS-BASEL ,2021,v11,issue 7
显示于类别:	[中山醫學大學研究成果] 期刊論文

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