Incidence, characteristics and outcomes among inpatient, outpatient and emergency department with reported high critical serum potassium values

doi:10.1515/cclm-2020-1476

中山醫學大學機構典藏 CSMUIR > 中山醫學大學研究成果 > 期刊論文 > Item 310902500/23604

Please use this identifier to cite or link to this item: https://ir.csmu.edu.tw:8080/ir/handle/310902500/23604

Title:	Incidence, characteristics and outcomes among inpatient, outpatient and emergency department with reported high critical serum potassium values
Authors:	Kuo, WH;You, HL;Huang, WT;Lee, YT;Chiou, TTY;Ng, HY;Lee, CT
Keywords:	critical hyperkalemia;critical laboratory value;mortality;potassium
Date:	2021
Issue Date:	2022-08-05T09:39:59Z (UTC)
Publisher:	WALTER DE GRUYTER GMBH
ISSN:	1434-6621
Abstract:	Objectives: Severe hyperkalemia can cause life-threatening arrhythmia, cardiac arrest, or death. This study aimed to investigate the incidence and the associated factors relevant to critical hyperkalemia (>= 6 mmol/L) among inpatients, outpatients, and emergency department. Their clinical outcomes were also analyzed. Methods: All patients whose high serum potassium values had been reported as critical laboratory values in 2016 were enrolled. Their demographic data, comorbidities, clinical symptoms, biochemical data, and outcomes were reviewed and collected. The Charlson comorbidity score (CCS) and glomerular filtration rate (GFR) were computed to assess the comorbidity burden and renal function. Patients were divided into groups according to different settings, potassium and GFR levels, and their survival. Results: Of the 293,830 total serum potassium tests, 1,382 (0.47%) reports were listed as critical laboratory values. The average reply time was 6.3 min. Their mean age was 67.2 years, while the average GFR was 12.2 mL/min/1.73 m(2). The overall mortality rate was 34%. Patients in the emergency department had the highest incidence (0.92%), while inpatients had the worst outcome (51% mortality). The leading cause of mortality was septic shock. The fatal group had higher rates of clinical symptoms, higher potassium values, CCS, and eGFR (all p<0.05). Conclusions: Most of the responses for the reports were obtained within a short period of time. Patients with reported high critical serum potassium values were characterized by high rates of comorbidity, reduced eGFR, and mortality. The incidence, clinical manifestations, and outcomes varied in the different clinical settings.
URI:	http://dx.doi.org/10.1515/cclm-2020-1476 https://www.webofscience.com/wos/woscc/full-record/WOS:000663327700017 https://ir.csmu.edu.tw:8080/handle/310902500/23604
Relation:	CLINICAL CHEMISTRY AND LABORATORY MEDICINE ,2021,v59,issue 7, P1231-1237
Appears in Collections:	[中山醫學大學研究成果] 期刊論文

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